Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062239 | 0.87 | FFAR1 (0.47) | PRKCAPRKCDFFAR1KCNA5MMP1 | |
| SCHEMBL3075533 | 0.85 | FFAR1 (0.46) | PRKCAPRKCDFFAR1KCNA5MMP1 | |
| SCHEMBL3069012 | 0.84 | FFAR1 (0.47) | PRKCAPRKCDFFAR1KCNA5MMP1 | |
| SCHEMBL3074108 | 0.84 | FFAR1 (0.45) | PRKCAPRKCDFFAR1KCNA5MMP1 | |
| SCHEMBL6309088 | 0.83 | FFAR1 (0.45) | PRKCAPRKCDFFAR1KCNA5MMP1 | |
| SCHEMBL13093725 | 0.82 | FFAR1 (0.43) | PRKCAPRKCDFFAR1KCNA5MMP1 | |
| SCHEMBL3062258 | 0.82 | KCNA5 (0.45) | PRKCAPRKCDFFAR1KCNA5MMP1 | |
| SCHEMBL13093728 | 0.82 | FFAR1 (0.43) | PRKCAPRKCDFFAR1KCNA5MMP1 | |
| SCHEMBL3061843 | 0.82 | FFAR1 (0.43) | PRKCAPRKCDFFAR1KCNA5MMP1 | |
| SCHEMBL3079305 | 0.82 | FFAR1 (0.42) | PRKCAPRKCDFFAR1KCNA5MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | ATP CAPITAL LP | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277663-A1 | 3-Aryl-3-hydroxy-and 3-aryl-3-oxopropionic acid esters as fungicides | CYP21A2, HAO1, AHR | PRKCA 3943/4885PRKCD 3870/4885FFAR1 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.