SCHEMBL3079305

SCHEMBL3079305

O=C(OCc1cccc(C(F)(F)F)c1)C(c1ccsc1)C(O)c1cccnc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.42
KCNA5 P22460 2/20 0.41
PRKCA P17252 1/20 0.41
PRKCD Q05655 1/20 0.41
MMP1 P03956 1/20 0.39
MMP12 P39900 1/20 0.39
VNN1 O95497 1/20 0.38
LRRK2 Q5S007 1/20 0.37
KDR P35968 1/20 0.37
NR1D1 P20393 1/20 0.37
NR1H3 Q13133 1/20 0.37
EPHX1 P07099 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NR4A2 P43354 2/20 0.36
MEN1 O00255 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3062239 0.88 FFAR1 (0.47) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL3075512 0.85 FFAR1 (0.41) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL13093725 0.85 FFAR1 (0.43) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL13093728 0.85 FFAR1 (0.43) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL3061843 0.85 FFAR1 (0.43) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL3074108 0.85 FFAR1 (0.45) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL3069012 0.83 FFAR1 (0.47) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL6309762 0.82 PRKCA (0.46) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL3062258 0.81 KCNA5 (0.45) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL13093724 0.81 KCNA5 (0.43) FFAR1KCNA5PRKCAPRKCDMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100267555-A1 Fungicidal mixtures II BASF SE (DE) 2010-10-21 US claimed
EP-2222169-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2010-09-01 EP claimed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 WO claimed
US-20100267555-A1 Fungicidal mixtures II BASF SE (DE) 2010-10-21 US disclosed
EP-2222169-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2010-09-01 EP disclosed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267555-A1 Fungicidal mixtures II CBR3, CBR1, NOX3 FFAR1 556/4885KCNA5 605/4885PRKCA 4389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.