Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urethane SCHEMBL2793501 | 0.81 | ALOX15 (0.54) | ALOX15HCAR2LMNATSHRALDH1A1 | |
| SCHEMBL9853791 | 0.80 | TSHR (0.44) | ALOX15GABRR1GABRR2BLMGABRR3 | |
| SCHEMBL306251 | 0.80 | TSHR (0.44) | ALOX15GABRR1GABRR2BLMGABRR3 | |
| SCHEMBL2023097 | 0.80 | HCAR2 (0.47) | HCAR2GABRR1GABRR2BLMGABRR3 | |
| Maleic Acid SCHEMBL8337803 | 0.78 | ALOX15 (0.71) | ALOX15HCAR2GABRR1GABRR2BLM | |
| Fumaric Acid SCHEMBL8712024 | 0.78 | ALOX15 (0.71) | ALOX15HCAR2GABRR1GABRR2BLM | |
| Fumaric Acid SCHEMBL8337808 | 0.78 | ALOX15 (0.71) | ALOX15HCAR2GABRR1GABRR2BLM | |
| Urethane SCHEMBL812193 | 0.78 | ALOX15 (0.54) | ALOX15HCAR2LMNATSHRALDH1A1 | |
| Methacrylic Acid SCHEMBL4919048 | 0.77 | HCAR2 (0.42) | HCAR2LMNATSHRNPSR1ALDH1A1 | |
| Methacrylic Acid SCHEMBL3632983 | 0.77 | TSHR (0.38) | ALOX15GABRR1GABRR2BLMGABRR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881360-B2 | Process for producing a prosthesis and a prosthesis material | HERAEUS KULZER GMBH & CO. KG (DE) | 2005-04-19 | — | — | US | claimed |