Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.62 |
| ▸ | PPARD | Q03181 | 18/20 | 0.58 |
| ▸ | PPARG | P37231 | 16/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634100 | 0.85 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL14277966 | 0.83 | PPARA (0.68) | PPARAPPARDPPARG | |
| SCHEMBL6313960 | 0.83 | PPARD (0.54) | PPARAPPARDPPARG | |
| SCHEMBL6831351 | 0.83 | PPARA (0.49) | PPARAPPARDPPARG | |
| SCHEMBL5631972 | 0.83 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL14422850 | 0.83 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL14429344 | 0.81 | PPARA (0.47) | PPARAPPARDPPARG | |
| SCHEMBL5702292 | 0.80 | PPARA (0.69) | PPARAPPARDPPARG | |
| SCHEMBL5702319 | 0.80 | PPARA (0.46) | PPARAPPARDPPARG | |
| SCHEMBL5678630 | 0.80 | PPARA (0.42) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070532-A1 | Aryl compounds as modulators of PPARS and methods of treating metabolic disorders | KALYPSYS, INC. | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070532-A1 | Aryl compounds as modulators of PPARS and methods of treating metabolic disorders | PPARG, PPARA, PPARD | PPARA 2/4885PPARD 3/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.