Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 7/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 6/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxaloacetate SCHEMBL28674017 | 1.00 | CA4 (0.56) | CA4OR51E2FEN1ERCC5PTPN1 | |
| Oxaloacetate SCHEMBL9994508 | 0.97 | CA4 (0.60) | CA4OR51E2FEN1ERCC5PTPN1 | |
| Oxaloacetate SCHEMBL9782823 | 0.93 | CA4 (0.56) | CA4OR51E2FEN1ERCC5PTPN1 | |
| Oxaloacetate SCHEMBL29210051 | 0.93 | CA4 (0.56) | CA4OR51E2FEN1ERCC5PTPN1 | |
| Oxaloacetate SCHEMBL29098309 | 0.93 | CA4 (0.56) | CA4OR51E2FEN1ERCC5PTPN1 | |
| Oxaloacetate SCHEMBL31087912 | 0.93 | CA4 (0.62) | CA4OR51E2FEN1ERCC5PTPN1 | |
| Oxaloacetate SCHEMBL7632482 | 0.93 | CA4 (0.56) | CA4OR51E2FEN1ERCC5PTPN1 | |
| Oxaloacetate SCHEMBL31027133 | 0.93 | CA4 (0.56) | CA4OR51E2FEN1ERCC5PTPN1 | |
| Oxaloacetate SCHEMBL11328363 | 0.93 | CA4 (0.56) | CA4OR51E2FEN1ERCC5PTPN1 | |
| Oxaloacetate SCHEMBL1469849 | 0.93 | CA4 (0.62) | CA4OR51E2FEN1ERCC5PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102340-A1 | GENETICALLY ENGINEERED YEAST STRAINS PRODUCING MALIC ACID | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2026-05-15 | — | — | WO | disclosed |
| US-12522808-B2 | Modified polypeptide with attenuated activity of citrate synthase and method for producing L-amino acid using the same | CJ Chieljedang Corporation (KR) | 2026-01-13 | — | — | US | disclosed |
| US-20250290078-A1 | HMO PRODUCING MICROORGANISM WITH INCREASED ROBUSTNESS TOWARDS GLUCOSE GRADIENTS | DSM IP ASSETS B.V. (NL) | 2025-09-18 | — | — | US | disclosed |
| EP-4514989-A1 | HMO PRODUCING MICROORGANISM WITH INCREASED ROBUSTNESS TOWARDS GLUCOSE GRADIENTS | DSM IP Assets B.V. (NL) | 2025-03-05 | — | — | EP | disclosed |
| CN-119095975-A | HMO-producing microorganism with improved robustness to glucose gradients | 帝斯曼知识产权资产管理有限公司 | 2024-12-06 | — | — | CN | disclosed |
| US-20240182872-A1 | NOVEL CITRATE SYNTHASE VARIANT AND METHOD FOR PRODUCING L-AMINO ACIDS USING SAME | CJ CHEILJEDANG CORPORATION (KR) | 2024-06-06 | — | — | US | disclosed |
| CN-115175993-B | Novel modified polypeptide having reduced citrate synthase activity and method for producing L-amino acid using the same | CJ第一制糖株式会社 | 2024-06-04 | — | — | CN | disclosed |
| US-20240150731-A1 | NOVEL CITRATE SYNTHASE VARIANT AND METHOD FOR PRODUCING L-VALINE USING THE SAME | CJ CHEILJEDANG CORPORATION (KR) | 2024-05-09 | — | — | US | disclosed |
| US-20240150730-A1 | NOVEL CITRATE SYNTHASE VARIANT AND METHOD FOR PRODUCING O-ACETYL-L-HOMOSERINE OR L-METHIONINE USING SAME | CJ CHEILJEDANG CORPORATION (KR) | 2024-05-09 | — | — | US | disclosed |
| CN-112175895-B | Modified polypeptides having reduced citrate synthase activity and methods of producing L-amino acids using the same | CJ第一制糖株式会社 | 2024-05-03 | — | — | CN | disclosed |
| EP-1032403-A4 | NUTRITIONAL SUPPLEMENT FOR CEREBRAL METABOLIC INSUFFICIENCIES | BLASS JOHN P (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6599732-B1 | Nucleotide sequences coding phosphoenolpyruvate carboxylase for use in process carbon dioxide | ARCHER-DANIELS-MIDLAND COMPANY | 2003-07-29 | — | — | US | disclosed |
| US-20020151010-A1 | Regulation of carbon assimilation | ARCHER-DANIELS-MIDLAND COMPANY | 2002-10-17 | — | — | US | disclosed |
| EP-1196611-A1 | REGULATION OF CARBON ASSIMILATION | Archer-Daniels-Midland Company (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001000852-A1 | REGULATION OF CARBON ASSIMILATION | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2001-01-04 | — | — | WO | disclosed |
| EP-1032403-A1 | NUTRITIONAL SUPPLEMENT FOR CEREBRAL METABOLIC INSUFFICIENCIES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999021565-A1 | NUTRITIONAL SUPPLEMENT FOR CEREBRAL METABOLIC INSUFFICIENCIES | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-05-06 | — | — | WO | disclosed |
| US-5597548-A | METABOLISM TO ACETYL COENZYME A; MEASURING GLUTAMATE ENRICHMENT PATTERN | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1997-01-28 | — | — | US | disclosed |
| US-5413917-A | Carbon-13 label, nuclear magnetic resonance | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-05-09 | — | — | US | disclosed |
| WO-1992001937-A2 | METHOD OF DETERMINING SOURCES OF ACETYL-COA UNDER NONSTEADY-STATE CONDITIONS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-02-06 | — | — | WO | disclosed |