Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Oxaloacetate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.62 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.35 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 4/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxaloacetate SCHEMBL1469849 | 1.00 | CA4 (0.62) | CA4OR51E2CASP1FEN1ERCC5 | |
| Oxaloacetate SCHEMBL9994508 | 0.97 | CA4 (0.60) | CA4OR51E2CASP1FEN1ERCC5 | |
| Oxaloacetate SCHEMBL28674017 | 0.93 | CA4 (0.56) | CA4OR51E2CASP1FEN1ERCC5 | |
| Oxaloacetate SCHEMBL29210051 | 0.93 | CA4 (0.56) | CA4OR51E2CASP1FEN1ERCC5 | |
| Oxaloacetate SCHEMBL29098309 | 0.93 | CA4 (0.56) | CA4OR51E2CASP1FEN1ERCC5 | |
| Oxaloacetate SCHEMBL7632482 | 0.93 | CA4 (0.56) | CA4OR51E2CASP1FEN1ERCC5 | |
| Oxaloacetate SCHEMBL6310312 | 0.93 | CA4 (0.56) | CA4OR51E2CASP1FEN1ERCC5 | |
| Oxaloacetate SCHEMBL9782823 | 0.93 | CA4 (0.56) | CA4OR51E2CASP1FEN1ERCC5 | |
| Oxaloacetate SCHEMBL11328363 | 0.93 | CA4 (0.56) | CA4OR51E2CASP1FEN1ERCC5 | |
| Oxaloacetate SCHEMBL31027133 | 0.93 | CA4 (0.56) | CA4OR51E2CASP1FEN1ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121895186-B | Bio-based hydrophobic monomer, triple shape memory hydrogel and application thereof | SOOCHOW UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-122004340-A | Denatured milk proteins and methods of making same | 奶普利乐食品公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-118647276-A | Denatured milk proteins and methods of making same | 奶普利乐食品公司 | 2024-09-13 | — | — | CN | disclosed |