Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.64 |
| ▸ | PPARA | Q07869 | 14/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARG | P37231 | 8/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310485 | 0.87 | MCHR1 (0.84) | MCHR1PPARAPPARGEPHX2 | |
| SCHEMBL6204138 | 0.77 | MCHR1 (0.50) | MCHR1ALDH1A1 | |
| SCHEMBL12426654 | 0.74 | PPARA (0.57) | PPARAPPARDPPARGEPHX2 | |
| SCHEMBL6203321 | 0.73 | HSD17B2 (0.51) | MCHR1ALDH1A1HPGD | |
| SCHEMBL6221795 | 0.72 | S1PR1 (0.50) | MCHR1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6316880 | 0.72 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL2086621 | 0.71 | PPARA (0.69) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL5974323 | 0.71 | PPARA (0.72) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6221751 | 0.71 | MCHR1 (0.47) | MCHR1ALDH1A1HPGD | |
| SCHEMBL27077360 | 0.70 | TACR3 (0.55) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009815-A1 | 4-Aminoquinoline compounds | DEVITA ROBERT J (US) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009815-A1 | 4-Aminoquinoline compounds | MCHR1, MCHR2, MC5R | MCHR1 1/4885PPARA 4024/4885PPARD 3797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.