Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 14/20 | 0.84 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310347 | 0.87 | MCHR1 (0.64) | MCHR1EPHX2PPARGPPARA | |
| SCHEMBL6316880 | 0.85 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL6310467 | 0.80 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL6202397 | 0.78 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL6310770 | 0.75 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL6199667 | 0.73 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL6199666 | 0.73 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL6317633 | 0.72 | MCHR1 (0.81) | MCHR1ASIC3 | |
| SCHEMBL3158764 | 0.72 | EPHX2 (0.73) | EPHX2PPARGPPARALSSKDM1A | |
| SCHEMBL12426654 | 0.71 | PPARA (0.57) | EPHX2PPARGPPARALSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009815-A1 | 4-Aminoquinoline compounds | DEVITA ROBERT J (US) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009815-A1 | 4-Aminoquinoline compounds | MCHR1, MCHR2, MC5R | MCHR1 1/4885ASIC3 2061/4885EPHX2 3401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.