Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 17/20 | 0.65 |
| ▸ | ITGB2 | P05107 | 12/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 12/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6318688 | 0.92 | ITGAL (0.69) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6308792 | 0.86 | ITGAL (0.77) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL7619374 | 0.86 | ITGAL (0.77) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6310664 | 0.84 | ITGAL (0.44) | ITGALITGB2ICAM1OPRM1OPRK1 | |
| SCHEMBL6310624 | 0.82 | ITGB2 (0.42) | ITGALITGB2ICAM1KDM4E | |
| SCHEMBL6279117 | 0.80 | ITGAL (0.81) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL4283189 | 0.80 | ITGAL (1.00) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL4283196 | 0.80 | ITGAL (1.00) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6199480 | 0.78 | ITGAL (0.79) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6312238 | 0.78 | ITGAL (0.81) | ITGALITGB2ICAM1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |