Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 14/20 | 0.69 |
| ▸ | ITGB2 | P05107 | 9/20 | 0.69 |
| ▸ | ICAM1 | P05362 | 9/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310671 | 0.92 | ITGAL (0.65) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6199480 | 0.84 | ITGAL (0.79) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6312238 | 0.83 | ITGAL (0.81) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6202398 | 0.83 | ITGAL (0.72) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6568213 | 0.83 | ITGAL (0.72) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6318682 | 0.81 | ITGAL (0.45) | ITGALITGB2ICAM1HPGDCRBN | |
| SCHEMBL6197151 | 0.80 | ITGAL (0.68) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6279117 | 0.80 | ITGAL (0.81) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6196154 | 0.80 | ITGAL (0.76) | ITGALITGB2ICAM1HPGDKDM4E | |
| SCHEMBL6318679 | 0.80 | HTR2C (0.43) | ITGALITGB2ICAM1CRBNHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |