Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304431 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL6303894 | 0.87 | KDR (0.44) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL6304103 | 0.73 | GLP1R (0.52) | KDRLMNASMN1; SMN2KDM1AL3MBTL1 | |
| SCHEMBL2821331 | 0.72 | KMT2A (0.69) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL6303849 | 0.69 | GLP1R (0.67) | ALDH1A1MAPTKDM4EHSD17B10POLB | |
| SCHEMBL6311061 | 0.67 | KMT2A (0.62) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL6303670 | 0.67 | KMT2A (0.62) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL23110691 | 0.65 | KMT2A (0.56) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL11425111 | 0.65 | KMT2A (0.64) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL15537600 | 0.65 | KMT2A (0.59) | ALDH1A1KMT2AMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |