SCHEMBL6310977

SCHEMBL6310977

CCCCCCOP(=O)(OCl)OCl

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.60
LPAR3 Q9UBY5 8/20 0.57
LPAR2 Q9HBW0 6/20 0.57
LPAR1 Q92633 3/20 0.57
TSHR P16473 1/20 0.47
LMNA P02545 1/20 0.46
ESR1 P03372 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CDC25A P30304 1/20 0.46
AGTR1 P30556 1/20 0.46
AKT1 P31749 1/20 0.46
ADRA1A P35348 1/20 0.46
KCNH2 Q12809 1/20 0.46
LPAR5 Q9H1C0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29151411 1.00 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL27873808 1.00 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL9328369 1.00 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL7736725 1.00 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL1261033 1.00 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL25170777 1.00 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL251881 0.98 CYP3A4 (0.62) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL28608720 0.96 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL177766 0.96 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR
SCHEMBL11350922 0.96 CYP3A4 (0.60) CYP3A4LPAR3LPAR2LPAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6455665-B1 ETHYL OR HEXYL DICHLOROPHOSPHATE OR DICHLOROPHOSPHONATE REACTED WITH A POLYESTER PREPOLYMER GUILFORD PHARMACEUTICALS INC. 2002-09-24 US claimed
US-20020028911-A1 Ethyl or hexyl dichlorophosphate or dichlorophosphonate reacted with a polyester prepolymer EISAI INC. 2002-03-07 US claimed
WO-2002004544-A2 POLYMERS AND POLYMERIZATION PROCESSES GUILFORD PHARMACEUTICALS (US) 2002-01-17 WO claimed
EP-4730479-A2 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME Kyoto University (JP) 2026-04-22 EP disclosed
US-20250246685-A1 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME KYOTO UNIVERSITY (JP) 2025-07-31 US disclosed
EP-4428982-A1 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME Kyoto University (JP) 2024-09-11 EP disclosed
CN-118056309-A Flame-retardant nonaqueous electrolyte and secondary battery using same 国立大学法人京都大学 2024-05-17 CN disclosed
WO-2023079988-A1 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME 国立大学法人京都大学 2023-05-11 WO disclosed
US-20050238616-A1 Compositions for treatment of central nervous system neoplasms, and methods of making and using the same GUILFORD PHARMACEUTICALS, INC. (US) 2005-10-27 US disclosed
WO-2002005800-A9 COMPOSITIONS FOR SUSTAINED RELEASE OF ANALGESIC AGENTS, AND METHODS OF MAKING AND USING THE SAME GUILFORD PHARM INC (US) 2003-08-28 WO disclosed
WO-2003060799-A2 COMPOSITIONS FOR TREATMENT OF CENTRAL NERVOUS SYSTEM NEOPLASMS, AND METHODS OF MAKING AND USING THE SAME GUILFORD PHARMACEUTICALS, INC. (US) 2003-07-24 WO disclosed
US-20020041897-A1 Compositions for sustained release of antineoplastic taxanes, and methods of making and using the same GUILFORD PHARMACEUTICALS, INC. 2002-04-11 US disclosed
US-20020028911-A1 Ethyl or hexyl dichlorophosphate or dichlorophosphonate reacted with a polyester prepolymer EISAI INC. 2002-03-07 US disclosed
WO-2002005800-A2 COMPOSITIONS FOR SUSTAINED RELEASE OF ANALGESIC AGENTS, AND METHODS OF MAKING AND USING THE SAME GUILFORD PHARMACEUTICALS, INC. (US) 2002-01-24 WO disclosed
WO-2002003957-A2 COMPOSITIONS FOR SUSTAINED RELEASE OF ANTINEOPLASTIC TAXANES, AND METHODS OF MAKING AND USING THE SAME GUILFORD PHARMACEUTICALS, INC. (US) 2002-01-17 WO disclosed
WO-2002004544-A2 POLYMERS AND POLYMERIZATION PROCESSES GUILFORD PHARMACEUTICALS (US) 2002-01-17 WO disclosed
US-5646111-A Cyclic peptide antifungal Agents ELI LILLY AND COMPANY (US) 1997-07-08 US disclosed
WO-1996031228-A1 CYCLIC PEPTIDE ANTIFUNGAL AGENTS ELI LILLY AND COMPANY (US) 1996-10-10 WO disclosed
EP-0736541-A1 Cyclic hexapeptide antifungal agents ELI LILLY AND COMPANY (US) 1996-10-09 EP disclosed
US-5010201-A Process for the preparation of substituted 2-chloropyridines BAYER AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050238616-A1 Compositions for treatment of central nervous system neoplasms, and methods of making and using the same PMP22, EWSR1, MLLT1 CYP3A4 4804/4885LPAR3 1506/4885LPAR2 2181/4885
US-20020041897-A1 Compositions for sustained release of antineoplastic taxanes, and methods of making and using the same LPXN, PAICS, TYMP CYP3A4 4147/4885LPAR3 2371/4885LPAR2 2825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.