SCHEMBL6311010

SCHEMBL6311010

CC(C)c1nc2cc(Cl)c(Cl)cc2nc1S(=O)(=O)CC1CC1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6311017 0.77 GLP1R (1.00) GLP1R
SCHEMBL6307427 0.76 GLP1R (1.00) GLP1R
SCHEMBL6310949 0.75 GLP1R (0.73) GLP1R
SCHEMBL6306428 0.72 GLP1R (1.00) GLP1R
SCHEMBL6304275 0.67 GLP1R (0.52) GLP1R
SCHEMBL6310999 0.67 GLP1R (0.60) GLP1R
SCHEMBL6306943 0.67 GLP1R (0.53) GLP1R
SCHEMBL6307685 0.66 GLP1R (0.72) GLP1R
SCHEMBL6304109 0.66 GLP1R (1.00) GLP1R
SCHEMBL6304232 0.66 GLP1R (0.66) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6927214-B1 Non-peptide GLP-1 agonists NOVO NORDISK A/S (DK) 2005-08-09 US disclosed
EP-1147094-A1 NON-PEPTIDE GLP-1 AGONISTS NOVO NORDISK A/S (DK) 2001-10-24 EP disclosed
WO-2000042026-A1 NON-PEPTIDE GLP-1 AGONISTS NOVO NORDISK A/S (DK) 2000-07-20 WO disclosed