⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300786 | 0.73 | TLR4 (0.32) | — | |
| SCHEMBL6312866 | 0.67 | CYP1A2 (0.38) | — | |
| SCHEMBL238978 | 0.64 | — | — | |
| SCHEMBL8196111 | 0.64 | — | — | |
| SCHEMBL14208363 | 0.63 | — | — | |
| SCHEMBL3875145 | 0.63 | — | — | |
| SCHEMBL1358657 | 0.63 | ALDH1A1 (0.34) | — | |
| SCHEMBL14157769 | 0.62 | — | — | |
| SCHEMBL7834163 | 0.62 | TSHR (0.33) | — | |
| SCHEMBL9596829 | 0.62 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
| WO-1996016054-A1 | CYCLOALKENYL-N-HYDROXYUREAS | PFIZER PHARMACEUTICALS INC. (JP) | 1996-05-30 | — | — | WO | disclosed |
| US-4945160-A | Preparation of certain 7-substituted quinolones | WARNER-LAMBERT COMPANY (US) | 1990-07-31 | — | — | US | disclosed |