Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221754 | 1.00 | RECQL (0.47) | RECQLMCHR1ASIC3GAARAB9A | |
| SCHEMBL6204138 | 0.82 | MCHR1 (0.50) | MCHR1ASIC3RAB9AMEN1KMT2A | |
| SCHEMBL6203321 | 0.78 | HSD17B2 (0.51) | MCHR1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL6221751 | 0.78 | MCHR1 (0.47) | MCHR1ASIC3MEN1KMT2AKDM4E | |
| Chimanine A SCHEMBL8588818 | 0.73 | HPGD (0.59) | GAAKDM4EPDE10ALMNAMAPT | |
| SCHEMBL6201487 | 0.72 | CTSK (0.43) | MCHR1MEN1KMT2AKDM4EESR1 | |
| SCHEMBL4259484 | 0.71 | MCHR1 (0.62) | MCHR1GAARAB9AMEN1KMT2A | |
| SCHEMBL31587738 | 0.70 | ESR1 (0.58) | MCHR1GAAMEN1KMT2AKDM4E | |
| SCHEMBL30506314 | 0.69 | RECQL (0.77) | RECQLGAARAB9AMEN1KMT2A | |
| SCHEMBL1660322 | 0.69 | RECQL (0.77) | RECQLGAARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009815-A1 | 4-Aminoquinoline compounds | DEVITA ROBERT J (US) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009815-A1 | 4-Aminoquinoline compounds | MCHR1, MCHR2, MC5R | RECQL 530/4885MCHR1 1/4885ASIC3 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.