SCHEMBL6311574

SCHEMBL6311574

CC(C)(Nc1nc2cc(Cl)c(Cl)cc2nc1S(C)(=O)=O)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 19/20 0.69
CCNE2 O96020 1/20 0.40
CCNE1 P24864 1/20 0.40
CDK2 P24941 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31673865 0.82 GLP1R (1.00) GLP1R
SCHEMBL2555049 0.82 GLP1R (1.00) GLP1R
SCHEMBL6305960 0.77 GLP1R (0.74) GLP1R
SCHEMBL6307213 0.71 GLP1R (1.00) GLP1R
SCHEMBL6304253 0.71 GLP1R (1.00) GLP1R
SCHEMBL6305727 0.69 GLP1R (0.73) GLP1R
SCHEMBL6306869 0.68 GLP1R (0.72) GLP1R
SCHEMBL6311020 0.68 GLP1R (0.58) GLP1R
SCHEMBL6307043 0.67 GLP1R (0.68) GLP1R
SCHEMBL6305942 0.67 GLP1R (0.50) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6927214-B1 Non-peptide GLP-1 agonists NOVO NORDISK A/S (DK) 2005-08-09 US disclosed