Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 2/20 | 0.30 |
| ▸ | HTR3A | P46098 | 2/20 | 0.30 |
| ▸ | HTR6 | P50406 | 2/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6654557 | 0.89 | CHRM4 (0.37) | HRH3MCHR1 | |
| SCHEMBL6310382 | 0.85 | CKS1B (0.37) | KCNH2 | |
| SCHEMBL6319498 | 0.80 | PIK3CD (0.31) | PIK3CD | |
| SCHEMBL6311937 | 0.79 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL6311792 | 0.79 | AKT1 (0.40) | — | |
| SCHEMBL6319337 | 0.78 | CSNK1E (0.35) | PIK3CD | |
| SCHEMBL6312100 | 0.78 | MAPK8 (0.36) | HRH1KCNH2JAK2JAK3MAPK8 | |
| SCHEMBL6316795 | 0.77 | EIF4E (0.35) | HRH3KCNH2MAPK8BTKMRGPRX2 | |
| SCHEMBL6317942 | 0.77 | KMT2A (0.38) | CYP2D6HTR3APIK3CD | |
| SCHEMBL6313201 | 0.76 | MCHR1 (0.35) | MAPK8BTKMRGPRX2MAPK10MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | HRH3 3867/4885CYP2D6 1018/4885HRH1 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.