Pyridine

Pyridine

SCHEMBL6312380

C1=CCCC=C1.c1ccncc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL16735405 1.00 TSHR (0.56) TSHRNAPRTTDP1
Pyridine SCHEMBL6073862 0.97 TSHR (0.53) TSHRNAPRTTDP1
Pyridine SCHEMBL9510891 0.87 TSHR (0.64) TSHRNAPRTTDP1
Pyridine SCHEMBL4533918 0.84 TSHR (0.60) TSHRNAPRTTDP1
Pyridine SCHEMBL8413463 0.81 TSHR (0.56) TSHRNAPRTTDP1
Benzene SCHEMBL1907770 0.79 TP53 (0.30) TSHR
Pyridine SCHEMBL28185062 0.79
Pyridine SCHEMBL28470394 0.75
Benzene SCHEMBL5682283 0.75
Pyridine SCHEMBL2784730 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3768253-A1 DEUTERATED ANALOGS OF D-& X3B2;-HYDROXYBUTYRIC ACID AND USES THEREOF Concert Pharmaceuticals Inc. (US) 2021-01-27 EP disclosed
US-20210008018-A1 DEUTERATED ANALOGS OF D-BETA-HYDROXYBUTYRIC ACID AND USES THEREOF CONCERT PHARMACEUTICALS, INC. 2021-01-14 US disclosed
WO-2019183564-A1 DEUTERATED ANALOGS OF D-β-HYDROXYBUTYRIC ACID AND USES THEREOF CONCERT PHARMACEUTICALS, INC. (US) 2019-09-26 WO disclosed
CN-102206841-B Method for preparing aluminum film through electrodeposition of ionic liquid on the surface of aluminum-based composite material UNIV SHANGHAI JIAOTONG 2014-04-16 CN disclosed
CN-102206841-A Method for preparing aluminum film through electrodeposition of ionic liquid on the surface of aluminum-based composite material UNIV SHANGHAI JIAOTONG 2011-10-05 CN disclosed
US-20050192461-A1 Polyoxometallate catalysts and catalytic processes DAVIS MARK E (US) 2005-09-01 US disclosed
US-6914029-B2 Polyoxometallate catalysts and catalytic processes CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2005-07-05 US disclosed
EP-1439908-A1 POLYOXOMETALLATE CATALYSTS AND METHOD FOR THE PRODUCTION OF CARBOXYLIC ACIDS BY CATALYSED PARTIAL OXIDATION OF ALKANES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2004-07-28 EP disclosed
US-20030144550-A1 Polyoxometallate catalysts and catalytic processes CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-07-31 US disclosed
WO-2003039745-A1 POLYOXOMETALLATE CATALYSTS AND METHOD FOR THE PRODUCTION OF CARBOXYLIC ACIDS BY CATALYSED PARTIAL OXIDATION OF ALKANES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2003-05-15 WO disclosed
EP-0431870-A1 Amphotericin B derivatives Beecham Group p.l.c. (GB) 1991-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210008018-A1 DEUTERATED ANALOGS OF D-BETA-HYDROXYBUTYRIC ACID AND USES THEREOF HBB, HADHB, DBH TSHR 2767/4885NAPRT 1696/4885TDP1 1938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.