Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.62 |
| ▸ | GAA | P10253 | 11/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | GLA | P06280 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | APAF1 | O14727 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | STAT6 | P42226 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311835 | 0.84 | KDM4E (0.80) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL23335540 | 0.83 | KDM4E (0.71) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL31653888 | 0.82 | KDM4E (0.63) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL6311981 | 0.82 | KDM4E (0.66) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL6312748 | 0.77 | KDM4E (1.00) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL6311488 | 0.77 | KDM4E (1.00) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL6652217 | 0.75 | KDM4E (0.81) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL6649614 | 0.75 | KDM4E (0.91) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL6311878 | 0.75 | KDM4E (0.91) | KDM4EGAAALDH1A1MAPTHPGD | |
| SCHEMBL31653735 | 0.74 | KDM4E (1.00) | KDM4EGAAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015172196-A1 | HETEROCYCLIC COMPOUNDS AND USE OF SAME | MONASH UNIVERSITY (AU) | 2015-11-19 | — | — | WO | disclosed |
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | KDM4E 3360/4885GAA 58/4885ALDH1A1 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.