Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | HK1 | P19367 | 1/20 | 0.56 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311002 | 0.91 | NPSR1 (0.77) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL6311403 | 0.89 | NPSR1 (0.67) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL6317970 | 0.88 | SMN1; SMN2 (0.68) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL6317648 | 0.86 | NPSR1 (0.66) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL6310562 | 0.85 | NPSR1 (0.64) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL6310700 | 0.84 | NPSR1 (0.63) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL6310391 | 0.83 | MAPT (0.62) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL6310321 | 0.83 | NPSR1 (1.00) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL14728335 | 0.81 | NPSR1 (0.57) | NPSR1MAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL6309843 | 0.81 | MAPT (0.70) | NPSR1MAPTSMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | NPSR1 1531/4885MAPT 1694/4885SMN1; SMN2 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.