Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26732995 | 0.81 | PRMT5 (0.43) | PRMT5WDR77GSK3BCHEK1PIM1 | |
| SCHEMBL29426590 | 0.81 | PRMT5 (0.43) | PRMT5WDR77GSK3BCHEK1PIM1 | |
| SCHEMBL26732994 | 0.75 | PRMT5 (0.40) | PRMT5WDR77GSK3BCHEK1PIM1 | |
| SCHEMBL6313685 | 0.73 | PRMT5 (0.41) | PRMT5WDR77GSK3BCHEK1PIM1 | |
| SCHEMBL17824579 | 0.73 | PRMT5 (0.46) | PRMT5WDR77GSK3BCHEK1PIM1 | |
| SCHEMBL29480940 | 0.73 | PRMT5 (0.59) | PRMT5WDR77GSK3BALDH1A1SMN1; SMN2 | |
| SCHEMBL17825064 | 0.73 | PRMT5 (0.59) | PRMT5WDR77GSK3BALDH1A1SMN1; SMN2 | |
| SCHEMBL29480982 | 0.73 | PRMT5 (0.46) | PRMT5WDR77GSK3BCHEK1PIM1 | |
| SCHEMBL29426556 | 0.72 | PRMT5 (0.46) | PRMT5WDR77GSK3BCHEK1PIM1 | |
| SCHEMBL26732891 | 0.72 | PRMT5 (0.46) | PRMT5WDR77GSK3BCHEK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050033050-A1 | Phthalazinones and the use thereof in order to combat undesirable microorganisms | BAYER CROPSCIENCE AG (DE) | 2005-02-10 | — | — | US | disclosed |
| EP-1430035-A1 | PHTHALAZINONES AND THE USE THEREOF IN ORDER TO COMBAT UNDESIRABLE MICROORGANISMS | Bayer CropScience AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003024938-A1 | PHTHALAZINONES AND THE USE THEREOF IN ORDER TO COMBAT UNDESIRABLE MICROORGANISMS | BAYER CROPSCIENCE AG (DE) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033050-A1 | Phthalazinones and the use thereof in order to combat undesirable microorganisms | PGLS, DCXR, C5 | PRMT5 170/4885WDR77 641/4885GSK3B 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.