SCHEMBL6312923

SCHEMBL6312923

CCCc1nc2cc(Cl)c(Cl)cc2nc1S(=O)(=O)C(C)C

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 19/20 0.71
CXCR2 P25025 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6303925 0.83 GLP1R (1.00) GLP1R
SCHEMBL6310998 0.82 GLP1R (0.48) GLP1R
SCHEMBL6310949 0.75 GLP1R (0.73) GLP1R
SCHEMBL6306917 0.72 GLP1R (0.78) GLP1R
SCHEMBL6311397 0.72 GLP1R (0.60) GLP1R
SCHEMBL6307205 0.72 GLP1R (0.70) GLP1R
SCHEMBL6306903 0.71 GLP1R (0.68) GLP1R
SCHEMBL6306418 0.71 GLP1R (0.59) GLP1R
SCHEMBL6307488 0.71 GLP1R (0.59) GLP1R
SCHEMBL6306313 0.70 GLP1R (0.77) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6927214-B1 Non-peptide GLP-1 agonists NOVO NORDISK A/S (DK) 2005-08-09 US claimed
US-6927214-B1 Non-peptide GLP-1 agonists NOVO NORDISK A/S (DK) 2005-08-09 US disclosed
EP-1147094-A1 NON-PEPTIDE GLP-1 AGONISTS NOVO NORDISK A/S (DK) 2001-10-24 EP disclosed
WO-2000042026-A1 NON-PEPTIDE GLP-1 AGONISTS NOVO NORDISK A/S (DK) 2000-07-20 WO disclosed