Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 15/20 | 0.60 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304232 | 0.78 | GLP1R (0.66) | GLP1RTXNRD1 | |
| SCHEMBL6303925 | 0.76 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6312923 | 0.72 | GLP1R (0.71) | GLP1R | |
| SCHEMBL6306418 | 0.70 | GLP1R (0.59) | GLP1R | |
| SCHEMBL6307488 | 0.70 | GLP1R (0.59) | GLP1R | |
| SCHEMBL6305850 | 0.68 | GLP1R (0.41) | GLP1RMEN1KMT2A | |
| SCHEMBL6303699 | 0.66 | GLP1R (0.53) | GLP1RKMT2A | |
| SCHEMBL11283068 | 0.66 | GLP1R (0.74) | GLP1RMEN1KMT2A | |
| SCHEMBL6306917 | 0.66 | GLP1R (0.78) | GLP1R | |
| SCHEMBL6306313 | 0.64 | GLP1R (0.77) | GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |
| EP-1147094-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000042026-A1 | NON-PEPTIDE GLP-1 AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-20 | — | — | WO | disclosed |