Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | DKK1 | O94907 | 1/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208247 | 1.00 | MCHR1 (0.53) | MCHR1DRD4UGT2B7HSD11B1CYP2D6 | |
| SCHEMBL6187443 | 1.00 | MCHR1 (0.53) | MCHR1DRD4UGT2B7HSD11B1CYP2D6 | |
| SCHEMBL8983490 | 0.82 | UGT2B7 (0.52) | MCHR1DRD4UGT2B7HSD11B1CYP2D6 | |
| SCHEMBL31046817 | 0.82 | UGT2B7 (0.52) | MCHR1DRD4UGT2B7HSD11B1CYP2D6 | |
| SCHEMBL6331798 | 0.81 | OGA (0.54) | MAPTOGA | |
| SCHEMBL6946061 | 0.80 | CYP2D6 (0.68) | DRD4CYP2D6MBTD1L3MBTL3MC4R | |
| SCHEMBL1803482 | 0.80 | CYP2D6 (0.68) | DRD4CYP2D6MBTD1L3MBTL3MC4R | |
| Hydrochloric Acid SCHEMBL8786946 | 0.79 | CYP2D6 (0.66) | DRD4CYP2D6MBTD1L3MBTL3MC4R | |
| Hydrochloric Acid SCHEMBL11532334 | 0.79 | CYP2D6 (0.66) | DRD4CYP2D6MBTD1L3MBTL3MC4R | |
| SCHEMBL6206243 | 0.78 | HSD11B1 (0.57) | MCHR1DRD4UGT2B7HSD11B1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921821-B2 | Antagonists of melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | MCHR1 1/4885DRD4 828/4885UGT2B7 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.