Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 9/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 6/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.39 |
| ▸ | PRKCG | P05129 | 3/20 | 0.39 |
| ▸ | PRKCB | P05771 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 3/20 | 0.39 |
| ▸ | PRKCA | P17252 | 3/20 | 0.39 |
| ▸ | PRKCH | P24723 | 3/20 | 0.39 |
| ▸ | PRKCI | P41743 | 3/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6315327 | 0.78 | IGF1R (0.64) | KDRAURKAAURKBPTK2ZAP70 | |
| SCHEMBL6314234 | 0.76 | KDR (0.57) | KDRAURKAAURKBPTK2ZAP70 | |
| SCHEMBL27997729 | 0.72 | FYN (0.59) | KDRAURKAAURKBPTK2ZAP70 | |
| SCHEMBL6317955 | 0.72 | IGF1R (0.57) | KDRAURKAAURKBPTK2ZAP70 | |
| SCHEMBL6311694 | 0.70 | KDR (0.52) | KDRAURKAAURKBPTK2ZAP70 | |
| SCHEMBL6312589 | 0.70 | IGF1R (0.59) | KDRAURKAAURKBPTK2ZAP70 | |
| SCHEMBL6318895 | 0.69 | IGF1R (0.59) | KDRAURKAAURKBPTK2ZAP70 | |
| SCHEMBL6419728 | 0.68 | KDR (0.49) | KDRAURKAAURKBPTK2EGFR | |
| SCHEMBL2205447 | 0.68 | IGF1R (0.63) | KDRAURKAAURKBPDGFRBPTK2 | |
| SCHEMBL6312279 | 0.68 | EGFR (0.39) | EGFRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979749-B2 | Catalytic process for the production of 3,3′, 4,4′-tetraminobiphenyl | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-12-27 | — | — | US | claimed |
| US-20050215823-A1 | NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | claimed |
| US-6979749-B2 | Catalytic process for the production of 3,3′, 4,4′-tetraminobiphenyl | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-12-27 | — | — | US | disclosed |
| US-6939874-B2 | Substituted pyrimidinyl derivatives and methods of use | AMGEN INC. (US) | 2005-09-06 | — | — | US | disclosed |
| US-20040063705-A1 | Substituted pyrimidinyl derivatives and methods of use | AMGEN INC. | 2004-04-01 | — | — | US | disclosed |
| EP-0369420-B1 | PROCESS FOR PREPARING 4,4'-DINITRODIPHENYL AMINE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0369420-A1 | Process for preparing 4,4'-dinitrodiphenyl amine | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0330591-A1 | Process for preparing aromatic carbamates | RHONE-POULENC CHIMIE (FR) | 1989-08-30 | — | — | EP | disclosed |
| EP-0125169-B1 | LIQUID COMPOSITION CONTAINING DIISOCYANATES WITH A DIPHENYL METHANE STRUCTURE, AND PROCESS FOR ITS PREPARATION | ELF ATOCHEM S.A. (FR) | 1987-10-07 | — | — | EP | disclosed |
| EP-0149388-B1 | ISOCYANATE COMPOSITION HAVING A LOW MELTING POINT WITH A DIPHENYL ETHANE STRUCTURE, PROCESS FOR THE PREPARATION THEREOF; USE FOR THE FABRICATION OF POLYURETHANES | ELF ATOCHEM S.A. (FR) | 1987-08-12 | — | — | EP | disclosed |
| EP-0078729-B1 | PROCESS FOR PREPARING AROMATIC ISOCYANATES BY CARBONYLATION OF NITRO COMPOUNDS IN THE PRESENCE OF SUPPORTED CATALYSTS PREPARED FROM HETEROPOLYMETALLIC COMPLEXES | RHONE-POULENC CHIMIE DE BASE (FR) | 1986-01-08 | — | — | EP | disclosed |
| EP-0045710-B1 | PROCESS FOR THE SELECTIVE PREPARATION OF META-CHLORINATED ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1984-07-04 | — | — | EP | disclosed |
| EP-0078729-A1 | Process for preparing aromatic isocyanates by carbonylation of nitro compounds in the presence of supported catalysts prepared from heteropolymetallic complexes | RHONE-POULENC CHIMIE DE BASE (FR) | 1983-05-11 | — | — | EP | disclosed |
| EP-0022387-B1 | PROCESS FOR THE PREPARATION OF BENZENE DERIVATIVES BY THE REACTION OF AN ACTIVATED HALOBENZENE WITH AN ORGANIC COMPOUND CONTAINING AN OXYGEN OR SULPHUR ANION | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-01-05 | — | — | EP | disclosed |
| EP-0015220-B1 | PROCESS FOR THE PREPARATION OF META-CHLORO ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1982-05-12 | — | — | EP | disclosed |
| EP-0045709-A1 | Process for the preparation of meta-chlorinated anilines | RHONE-POULENC AGROCHIMIE (FR) | 1982-02-10 | — | — | EP | disclosed |
| EP-0045710-A1 | Process for the selective preparation of meta-chlorinated anilines | RHONE-POULENC AGROCHIMIE (FR) | 1982-02-10 | — | — | EP | disclosed |
| EP-0015219-B1 | PROCESS FOR THE PREPARATION OF META-CHLORO ANILINES | RHONE-POULENC AGROCHIMIE (FR) | 1981-10-28 | — | — | EP | disclosed |
| EP-0015220-A1 | Process for the preparation of meta-chloro anilines | RHONE-POULENC AGROCHIMIE (FR) | 1980-09-03 | — | — | EP | disclosed |
| EP-0015219-A1 | Process for the preparation of meta-chloro anilines | RHONE-POULENC AGROCHIMIE (FR) | 1980-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063705-A1 | Substituted pyrimidinyl derivatives and methods of use | DPYD, TYMP, TPMT | KDR 2148/4885AURKA 2306/4885AURKB 1715/4885 |
| US-20050215823-A1 | NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL | NNMT, CBR3, POR | KDR 1203/4885AURKA 1034/4885AURKB 2487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.