Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6190225 | 0.94 | PRKDC (0.56) | PRKDCMCHR1KCNH2 | |
| SCHEMBL6187750 | 0.81 | LMNA (0.52) | PRKDCKDM4ELMNAMCHR1TSHR | |
| SCHEMBL6232398 | 0.79 | MCHR1 (0.66) | MCHR1TSHRKCNH2 | |
| SCHEMBL31060836 | 0.77 | PRKDC (1.00) | PRKDC | |
| SCHEMBL6187458 | 0.76 | MCHR1 (0.59) | KDM4EMCHR1TSHRKCNH2 | |
| SCHEMBL6187903 | 0.75 | MCHR1 (0.80) | KDM4ELMNAMCHR1TSHRKCNH2 | |
| SCHEMBL6187899 | 0.75 | MCHR1 (0.80) | KDM4ELMNAMCHR1TSHRKCNH2 | |
| SCHEMBL6190082 | 0.75 | MCHR1 (0.58) | MCHR1TSHRKCNH2 | |
| SCHEMBL6189522 | 0.75 | MCHR1 (0.80) | LMNAMCHR1TSHRKCNH2 | |
| SCHEMBL31061138 | 0.74 | PRKDC (0.70) | PRKDCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921821-B2 | Antagonists of melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2005-07-26 | — | — | US | claimed |
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | claimed |
| US-6921821-B2 | Antagonists of melanin concentrating hormone receptor | ABBOTT LABORATORIES (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MILLENNIUM PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106645-A1 | Antagonists of melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | PRKDC 4832/4885KDM4E 1548/4885LMNA 3781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.