SCHEMBL6313221

SCHEMBL6313221

CCCCNC(=S)Sc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 7/20 0.50
MAPT P10636 4/20 0.50
GAA P10253 3/20 0.50
NPSR1 Q6W5P4 2/20 0.50
ALOX12 P18054 1/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
LMNA P02545 4/20 0.49
PAX8 Q06710 1/20 0.49
TSHR P16473 1/20 0.46
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
IDO1 P14902 1/20 0.44
NAAA Q02083 1/20 0.42
MEN1 O00255 1/20 0.41
HPGD P15428 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
EPHX1 P07099 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27461463 0.98 HTT (0.49) HTTMAPTGAANPSR1ALOX12
SCHEMBL27712999 0.92 NAAA (0.50) HTTMAPTGAANPSR1ALOX12
SCHEMBL27693154 0.92 NAAA (0.50) HTTMAPTGAANPSR1ALOX12
SCHEMBL6305069 0.89 KMT2A (0.51) HTTMAPTGAANPSR1ALOX12
SCHEMBL15105228 0.87 IDO1 (0.43) IDO1NAAA
SCHEMBL1425589 0.82 KDM4A (0.46) HTTMAPTGAANPSR1ALOX12
SCHEMBL31087287 0.81 MAPT (0.55) HTTMAPTGAANPSR1ALOX12
SCHEMBL28057361 0.80 KDM4A (0.45) HTTMAPTGAANPSR1ALOX12
SCHEMBL6319495 0.77 IDO1 (0.51) HTTMAPTGAANPSR1ALOX12
SCHEMBL27810502 0.77 IDO1 (0.42) MAPTGAAALOX12KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858568-B2 Metal lubricants containing a bridge complex MEC INTERNATIONAL CORPORATION (JP) 2005-02-22 US claimed
US-20020123435-A1 Metal lubricants containing a bridge complex MEC INTERNATIONAL CORPORATION 2002-09-05 US claimed
CN-107922698-A Ethene-alpha-olefin based copolymer rubber, rubber composition, the method for manufacturing ethene-alpha-olefin based copolymer rubber 住友化学株式会社 2018-04-17 CN disclosed
CN-103945948-B Foam flotation method 塞特克技术公司 2017-08-25 CN disclosed
CN-104093492-B Froth flotation processes 塞特克技术公司 2017-05-10 CN disclosed