SCHEMBL6313308

SCHEMBL6313308

CCCC(C)CSc1nnc(N)s1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
RAB9A P51151 4/20 0.44
NPC1 O15118 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
FBP1 P09467 1/20 0.42
GAA P10253 3/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 1/20 0.38
ALOX15 P16050 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
HSD17B10 Q99714 1/20 0.38
POLB P06746 1/20 0.38
USP2 O75604 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8477437 0.80 ALDH1A1 (0.62) ALDH1A1RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3549799 0.77 ALDH1A1 (0.58) ALDH1A1RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL12856889 0.76 ALDH1A1 (0.56) ALDH1A1RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL8479039 0.74 ALDH1A1 (0.73) ALDH1A1RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL15277959 0.74 ALDH1A1 (0.61) ALDH1A1RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL94572 0.74
SCHEMBL9579065 0.72 ALDH1A1 (0.86) ALDH1A1RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL3907899 0.70 ALDH1A1 (0.50) ALDH1A1MAPTHPGDGAAMAPK1
SCHEMBL15362563 0.69 ALDH1A1 (0.68) ALDH1A1RAB9ANPC1SMN1; SMN2LMNA
SCHEMBL4399146 0.69 ALDH1A1 (1.00) ALDH1A1RAB9ANPC1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6887656-B2 Color photographic element containing improved heterocyclic speed enhancing compound EASTMAN KODAK COMPANY (US) 2005-05-03 US disclosed
US-20040142289-A1 COLOR PHOTOGRAPHIC ELEMENT CONTAINING IMPROVED HETEROCYCLIC SPEED ENHANCING COMPOUND EASTMAN KODAK COMPANY 2004-07-22 US disclosed
EP-1439416-A1 Color photographic element containing improved heterocyclic speed enhancing compound EASTMAN KODAK COMPANY (US) 2004-07-21 EP disclosed