Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317725 | 1.00 | CES2 (0.58) | CES2CES1PARP1MEN1KMT2A | |
| SCHEMBL4078123 | 0.93 | CES2 (0.65) | CES2CES1PARP1MEN1KMT2A | |
| SCHEMBL6319924 | 0.83 | CES1 (0.44) | CES2CES1PARP1MEN1KMT2A | |
| SCHEMBL29623677 | 0.77 | ATM (0.71) | CES2CES1PARP1MEN1KMT2A | |
| SCHEMBL3834026 | 0.77 | ATM (0.71) | CES2CES1PARP1MEN1KMT2A | |
| SCHEMBL29174153 | 0.77 | CES2 (0.54) | CES2CES1PARP1MEN1KMT2A | |
| SCHEMBL6312637 | 0.77 | NPC1 (0.48) | CES2CES1MEN1KMT2AKCNK3 | |
| SCHEMBL31448095 | 0.76 | CES2 (0.58) | CES2CES1PARP1MEN1KMT2A | |
| SCHEMBL16955426 | 0.76 | CES2 (0.58) | CES2CES1PARP1MEN1KMT2A | |
| SCHEMBL13950378 | 0.76 | CES2 (0.71) | CES2CES1PARP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924301-B1 | Composition for treating or preventing arrhythmia | SHIONOGI & CO., LTD. (JP) | 2005-08-02 | — | — | US | disclosed |
| EP-1240906-A1 | PREVENTIVES OR REMEDIES FOR ARRHYTHMIA | SHIONOGI & CO., LTD. (JP) | 2002-09-18 | — | — | EP | disclosed |