Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313788 | 0.75 | KDM4E (0.58) | KDM4ECYP11B1CYP11B2GRIN2DGRIN3B | |
| SCHEMBL24352139 | 0.75 | KDM4E (0.96) | KDM4ECYP11B1CYP11B2GRIN2DGRIN3B | |
| SCHEMBL28223160 | 0.75 | KDM4E (0.58) | KDM4ECYP11B1CYP11B2GRIN2DGRIN3B | |
| SCHEMBL6313781 | 0.73 | KDM4E (0.56) | KDM4ECYP11B1CYP11B2GRIN2DGRIN3B | |
| SCHEMBL7853978 | 0.68 | KDM4E (0.50) | KDM4ECYP11B1CYP11B2GRIN2DGRIN3B | |
| SCHEMBL27677697 | 0.68 | KDM4E (0.50) | KDM4ECYP11B1CYP11B2GRIN2DGRIN3B | |
| SCHEMBL2200491 | 0.67 | SMN1; SMN2 (0.36) | KDM4EGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL19173447 | 0.66 | KDM4E (0.47) | KDM4EHSD11B1EPHX2ALDH1A1L3MBTL1 | |
| SCHEMBL9906604 | 0.66 | KDM4E (0.47) | KDM4ECYP11B1CYP11B2GRIN2DGRIN3B | |
| SCHEMBL5949128 | 0.62 | MEN1 (0.30) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014810-A1 | Use of substituted 2 phenylbenzimidazoles as medicaments | GLP1R, GIPR, GCGR | KDM4E 2371/4885CYP11B1 525/4885CYP11B2 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.