Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 10/20 | 0.41 |
| ▸ | CDK1 | P06493 | 9/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.36 |
| ▸ | SELE | P16581 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320256 | 0.87 | MAPKAPK2 (0.43) | MAPKAPK2CDK1PRKD1L3MBTL1TDP1 | |
| SCHEMBL6312783 | 0.85 | MAPKAPK2 (0.49) | MAPKAPK2CDK1PRKD1L3MBTL1TDP1 | |
| SCHEMBL6319365 | 0.84 | MAPKAPK2 (0.43) | MAPKAPK2CDK1PRKD1L3MBTL1TDP1 | |
| SCHEMBL6312286 | 0.83 | MAPKAPK2 (0.40) | MAPKAPK2CDK1PRKD1L3MBTL1TDP1 | |
| SCHEMBL6314257 | 0.82 | MAPKAPK2 (0.57) | MAPKAPK2CDK1PRKD1L3MBTL1TDP1 | |
| SCHEMBL6320565 | 0.79 | PIK3R1 (0.40) | MAPKAPK2CDK1PRKD1ALDH1A1MAPT | |
| SCHEMBL6312961 | 0.76 | MAPKAPK2 (0.46) | MAPKAPK2CDK1PRKD1L3MBTL1TDP1 | |
| SCHEMBL6318665 | 0.75 | MAPKAPK2 (0.42) | MAPKAPK2CDK1PRKD1L3MBTL1TDP1 | |
| SCHEMBL6312661 | 0.74 | MAPKAPK2 (0.55) | MAPKAPK2CDK1PRKD1L3MBTL1TDP1 | |
| SCHEMBL6313342 | 0.72 | MAPKAPK2 (0.40) | MAPKAPK2CDK1PRKD1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250765-A1 | Diazepinones as antiviral agents | CHO HIDETSURA | 2005-11-10 | — | — | US | claimed |
| US-20040116410-A1 | Diazepinones as antiviral agents | CHO HIDETSURA (JP) | 2004-06-17 | — | — | US | claimed |
| US-20050250765-A1 | Diazepinones as antiviral agents | CHO HIDETSURA | 2005-11-10 | — | — | US | disclosed |
| US-20040116410-A1 | Diazepinones as antiviral agents | CHO HIDETSURA (JP) | 2004-06-17 | — | — | US | disclosed |
| WO-2002014324-A2 | DIAZEPINONES AS ANTIVIRAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250765-A1 | Diazepinones as antiviral agents | ZC3HAV1, ECI1, ZC3HAV1L | MAPKAPK2 3952/4885CDK1 274/4885PRKD1 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.