Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A2 | O00482 | 1/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139591 | 0.81 | ALDH1A1 (0.49) | NR5A2NR5A1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL1719554 | 0.79 | NR5A2 (0.48) | NR5A2NR5A1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL235651 | 0.75 | NR5A2 (0.51) | NR5A2NR5A1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL28258344 | 0.75 | NR5A2 (0.43) | NR5A2NR5A1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL8028498 | 0.75 | HSPA5 (0.55) | NR5A2NR5A1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL29404283 | 0.75 | HSPA5 (0.55) | NR5A2NR5A1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL7966200 | 0.74 | NR5A2 (0.50) | NR5A2NR5A1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL17500076 | 0.73 | ALDH1A1 (0.48) | NR5A2NR5A1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL11312390 | 0.73 | NR5A2 (0.49) | NR5A2NR5A1ALDH1A1MAPK1NPSR1 | |
| SCHEMBL30800914 | 0.73 | NR5A2 (0.49) | NR5A2NR5A1ALDH1A1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050131177-A1 | 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | KRAMER ANDREAS (SE) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131177-A1 | 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | PYM1, PTGER1, CBR1 | NR5A2 3391/4885NR5A1 3117/4885ALDH1A1 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.