Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803781 | 0.90 | EDNRB (1.00) | EDNRB | |
| SCHEMBL8698300 | 0.89 | EDNRB (0.80) | EDNRB | |
| SCHEMBL8805492 | 0.87 | EDNRB (0.81) | EDNRB | |
| SCHEMBL8804652 | 0.87 | EDNRB (1.00) | EDNRB | |
| SCHEMBL8804018 | 0.86 | EDNRB (0.86) | EDNRB | |
| SCHEMBL8698304 | 0.86 | EDNRB (0.75) | EDNRB | |
| SCHEMBL8805398 | 0.85 | EDNRB (1.00) | EDNRB | |
| SCHEMBL6320723 | 0.85 | EDNRB (0.92) | EDNRB | |
| SCHEMBL6315724 | 0.85 | EDNRB (0.76) | EDNRB | |
| SCHEMBL8804680 | 0.84 | EDNRB (0.86) | EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014769-A1 | Use of endothelin receptor antogonists for the treatment of tumour diseases | MERCK PATENT GMBH (DE) | 2005-01-20 | — | — | US | claimed |
| US-6867212-B2 | 6-(1-fluoroethyl)-5-iodo-4-aminopyrimidine compounds process for preparation of the same and pest controllers for agricultural and horticultural use | UBE INDUSTRIES, LTD. (JP) | 2005-03-15 | — | — | US | disclosed |
| US-20050014769-A1 | Use of endothelin receptor antogonists for the treatment of tumour diseases | MERCK PATENT GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
| US-20040063945-A1 | 6-(1-fluoroethyl)-5-iodo-4-aminopyrimidine compounds process for preparation of the same and pest controllers for agricultural and horticultural use | MAKHTESHIM CHEMICAL WORKS LTD. (IL) | 2004-04-01 | — | — | US | disclosed |
| EP-1357113-A1 | 6-(1-FLUOROETHYL)-5-IODO-4-AMINOPYRIMIDINE COMPOUNDS, PROCESS FOR PREPARATION OF THE SAME, AND PEST CONTROLLERS FOR AGRICULTURAL AND HORTICULTURAL USE | Ube Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014769-A1 | Use of endothelin receptor antogonists for the treatment of tumour diseases | EDNRA, EDNRB, ECE1 | EDNRB 2/4885 |
| US-20040063945-A1 | 6-(1-fluoroethyl)-5-iodo-4-aminopyrimidine compounds process for preparation of the same and pest controllers for agricultural and horticultural use | CYP4X1, IPO5, IP6K1 | EDNRB 4830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.