Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803781 | 0.87 | EDNRB (1.00) | EDNRB | |
| SCHEMBL6314933 | 0.87 | EDNRB (1.00) | EDNRB | |
| SCHEMBL8805492 | 0.84 | EDNRB (0.81) | EDNRB | |
| SCHEMBL8805398 | 0.83 | EDNRB (1.00) | EDNRB | |
| SCHEMBL8804680 | 0.82 | EDNRB (0.86) | EDNRB | |
| SCHEMBL8806259 | 0.81 | EDNRB (0.84) | EDNRB | |
| SCHEMBL8804018 | 0.79 | EDNRB (0.86) | EDNRB | |
| SCHEMBL8698300 | 0.76 | EDNRB (0.80) | EDNRB | |
| SCHEMBL8580666 | 0.76 | EDNRB (0.63) | EDNRB | |
| SCHEMBL6320723 | 0.75 | EDNRB (0.92) | EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700807-A | Endothelin receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-23 | — | — | US | disclosed |
| EP-0755934-A1 | Endothelin receptor antagonists | MERCK PATENT GmbH (DE) | 1997-01-29 | — | — | EP | disclosed |