Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 12/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766400 | 0.81 | RBP4 (0.68) | RBP4MEN1KMT2ALMNATSHR | |
| SCHEMBL766256 | 0.79 | RBP4 (0.79) | RBP4MEN1KMT2ALMNATSHR | |
| SCHEMBL766270 | 0.78 | RBP4 (0.78) | RBP4MEN1KMT2ALMNATSHR | |
| SCHEMBL632049 | 0.78 | RBP4 (0.77) | RBP4MEN1KMT2ALMNATSHR | |
| SCHEMBL3721337 | 0.77 | RBP4 (0.79) | RBP4MEN1KMT2ALMNATSHR | |
| SCHEMBL631988 | 0.77 | RBP4 (1.00) | RBP4MEN1KMT2ALMNATSHR | |
| SCHEMBL27873790 | 0.77 | RBP4 (0.73) | RBP4MEN1KMT2ALMNATSHR | |
| SCHEMBL3718601 | 0.77 | RBP4 (0.69) | RBP4MEN1KMT2ALMNATSHR | |
| SCHEMBL631529 | 0.76 | RBP4 (0.74) | RBP4MEN1KMT2ALMNATSHR | |
| SCHEMBL27873714 | 0.75 | RBP4 (0.72) | RBP4MEN1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419413-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2012-02-22 | — | — | EP | disclosed |