Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | POLG | P54098 | 1/20 | 0.33 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234866 | 0.91 | ST6GAL1 (0.32) | POLBST6GAL1 | |
| SCHEMBL5396749 | 0.91 | POLB (0.31) | POLBST6GAL1 | |
| SCHEMBL6730011 | 0.89 | POLB (0.30) | POLB | |
| SCHEMBL5200194 | 0.88 | POLB (0.37) | POLBPOLGST6GAL1 | |
| SCHEMBL5200171 | 0.85 | POLB (0.40) | POLBPOLGST6GAL1 | |
| SCHEMBL6574062 | 0.84 | — | — | |
| SCHEMBL6318268 | 0.83 | CHKA (0.37) | — | |
| SCHEMBL6236139 | 0.80 | POLB (0.36) | POLBPOLGST6GAL1 | |
| SCHEMBL6573453 | 0.80 | POLB (0.36) | POLBPOLGST6GAL1 | |
| SCHEMBL4350930 | 0.79 | ST6GAL1 (0.34) | POLBPOLGST6GAL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967247-B2 | Deprotection of phosphorus in oligonucleotide synthesis | ISIS PHARMACEUTICALS, INC. (US) | 2005-11-22 | — | — | US | disclosed |
| US-20040024194-A1 | Deprotection of phosphorus in oligonucleotide synthesis | ISIS PHARMACEUTICALS, INC. | 2004-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040024194-A1 | Deprotection of phosphorus in oligonucleotide synthesis | OR51E2, PNKP, RNGTT | POLB 86/4885POLG 336/4885ST6GAL1 1575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.