Sugi Predict

Sugi Predict / Compounds / SCHEMBL6316874

SCHEMBL6316874

SCHEMBL6316874

NC(=O)c1c(-c2ccncc2)noc1NC(=O)c1ccco1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IKBKE Q14164 1/20 0.57
▸ TBK1 Q9UHD2 1/20 0.57
▸ ADORA3 P0DMS8 1/20 0.51
▸ ADORA2A P29274 1/20 0.51
▸ ADORA2B P29275 1/20 0.51
▸ ADORA1 P30542 1/20 0.51
▸ MAPT P10636 6/20 0.50
▸ POLB P06746 3/20 0.50
▸ HSD17B10 Q99714 3/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ MEN1 O00255 1/20 0.50
▸ CLK1 P49759 1/20 0.50
▸ MCL1 Q07820 1/20 0.50
▸ NPC1 O15118 5/20 0.48
▸ RAB9A P51151 5/20 0.48
▸ LMNA P02545 3/20 0.48
▸ TP53 P04637 3/20 0.48
▸ TDP1 Q9NUW8 1/20 0.45
▸ ALDH1A1 P00352 5/20 0.45
▸ SMN1; SMN2 Q16637 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6316823 0.87 POLB (0.54) IKBKETBK1ADORA3ADORA2AADORA1
SCHEMBL6315475 0.85 KIT (0.50) IKBKETBK1MAPTPOLBHSD17B10
SCHEMBL27591719 0.83 IKBKE (0.50) IKBKETBK1ADORA3ADORA2AADORA2B
SCHEMBL6315901 0.82 MAPT (0.54) IKBKETBK1ADORA3ADORA1MAPT
SCHEMBL6319728 0.81 TBK1 (0.52) TBK1POLBHSD17B10KMT2AMEN1
SCHEMBL6318669 0.81 SMN1; SMN2 (0.53) IKBKETBK1ADORA3ADORA2AADORA2B
SCHEMBL6314886 0.80 MAPT (0.50) IKBKETBK1ADORA3ADORA2AADORA2B
SCHEMBL6317649 0.79 SMN1; SMN2 (0.54) TBK1POLBHSD17B10KMT2AMEN1
SCHEMBL6316571 0.78 TYK2 (0.53) MAPTPOLBHSD17B10KMT2AMEN1
SCHEMBL6317088 0.78 HTT (0.53) MAPTPOLBHSD17B10KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146522-A Bipyridine bridged binuclear cuprous luminescent material and application thereof in fluorescence sensing of VOCs 中国计量大学 2024-06-07 — — CN claimed
CN-118108759-A Binuclear cuprous complex luminescent material and fluorescent sensing application of binuclear cuprous complex luminescent material to VOC (volatile organic compounds) such as acetophenone 中国计量大学 2024-05-31 — — CN claimed
CN-111848697-B Cobalt complex, preparation method thereof and application of cobalt complex as anti-ferromagnetic material 武汉大学 2023-12-22 — — CN claimed
CN-116970008-A Nickel complex of N-acetyl-D-phenylalanine, preparation method and application thereof 河北师范大学 2023-10-31 — — CN claimed
CN-116284063-A Nitrogen-containing carboxylic acid transition metal complex and preparation method and application thereof 延安大学 2023-06-23 — — CN claimed
CN-114752070-B Photoresponse intelligent material and preparation method thereof 江西科技师范大学 2023-03-21 — — CN claimed
CN-115651001-A Complex structure regulation and control method based on azo dicarboxylic acid-based ligand 辽宁石油化工大学 2023-01-31 — — CN claimed
CN-112877058-B Supermolecule fluorescent compound and preparation method and application thereof 四川轻化工大学 2022-08-12 — — CN claimed
CN-113698622-A Methyl side chain-containing dipicolinic acid and 1, 10-phenanthroline-constructed terbium coordination polymer and preparation method thereof 桂林理工大学 2021-11-26 — — CN claimed
CN-113402718-A Zinc complex constructed by terephthalic acid containing trifluoromethyl side chain and 4, 4' -bipyridyl and preparation method thereof 桂林理工大学 2021-09-17 — — CN claimed
CN-110305172-B Cobalt phosphonate, preparation method thereof and application of cobalt phosphonate as wide-temperature-range proton conducting material 武汉大学 2020-09-01 — — CN claimed
CN-110372752-B Manganese complex with anti-ferromagnetism as well as preparation method and application thereof 武汉大学 2020-07-24 — — CN claimed
CN-110229193-B Nickel complex, preparation method thereof and application of nickel complex as proton conducting material 武汉大学 2020-06-30 — — CN claimed
CN-108794753-A A kind of BINAP and the orange-yellow phosphorescent light-emitting materials of the cuprous complex of bipyridyl mixture 中国计量大学 2018-11-13 — — CN claimed
CN-107778492-A A kind of Co (II) coordination polymer and its preparation method and application 重庆师范大学 2018-03-09 — — CN claimed
CN-107629218-A A kind of Ni（II）Coordination polymer and its preparation method and application 重庆师范大学 2018-01-26 — — CN claimed
CN-106750354-A A kind of m-nitro sulfonyl glycine manganese complex crystal and synthetic method 安顺学院 2017-05-31 — — CN claimed
US-20050059657-A1 Aminoisoxazole derivatives active as kinase inhibitors PFIZER ITALIA S.R.L. (IT) 2005-03-17 — — US claimed
EP-1435948-A1 AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-07-14 — — EP claimed
WO-2003013517-A1 AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS PHARMACIA ITALIA S.P.A. (IT) 2003-02-20 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050059657-A1 Aminoisoxazole derivatives active as kinase inhibitors MAP3K9, MAP3K19, MAP4K2 IKBKE 80/4885TBK1 73/4885ADORA3 1471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.