Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2486667 | 0.91 | ACE2 (0.42) | LMNAACE2ADH1BADH1CADH1A | |
| SCHEMBL2483906 | 0.91 | ACE2 (0.42) | LMNAACE2ADH1BADH1CADH1A | |
| SCHEMBL2485561 | 0.91 | ACE2 (0.42) | LMNAACE2ADH1BADH1CADH1A | |
| SCHEMBL23363677 | 0.82 | LMNA (0.74) | LMNAACE2BLMPTPN1MEN1 | |
| SCHEMBL672089 | 0.82 | LMNA (0.74) | LMNAACE2BLMPTPN1MEN1 | |
| SCHEMBL38655840 | 0.82 | LMNA (0.74) | LMNAACE2BLMPTPN1MEN1 | |
| SCHEMBL23672996 | 0.82 | LMNA (0.74) | LMNAACE2BLMPTPN1MEN1 | |
| SCHEMBL31509473 | 0.82 | LMNA (0.74) | LMNAACE2BLMPTPN1MEN1 | |
| SCHEMBL10959498 | 0.82 | LMNA (0.74) | LMNAACE2BLMPTPN1MEN1 | |
| SCHEMBL31509120 | 0.82 | LMNA (0.74) | LMNAACE2BLMPTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050152959-A1 | Use of a lysolipid for the preparation of a composition for transfection of a polynucleotide into a cell | TRANSGENE S. A. (FR) | 2005-07-14 | — | — | US | disclosed |
| EP-1465597-A2 | USE OF A LYSOLIPID FOR THE PREPARATION OF A COMPOSITION FOR TRANSFECTION OF A POLYNUCLEOTIDE INTO A CELL | TRANSGENE S.A. (FR) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003052095-A2 | USE OF A LYSOLIPID FOR THE PREPARATION OF A COMPOSITION FOR TRANSFECTION OF A POLYNUCLEOTIDE INTO A CELL | TRANSGENE S.A. (FR) | 2003-06-26 | — | — | WO | disclosed |
| US-4935520-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| EP-0108565-A2 | Phospholipids, their production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1984-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050152959-A1 | Use of a lysolipid for the preparation of a composition for transfection of a polynucleotide into a cell | LPCAT1, LPCAT3, LCLAT1 | LMNA 91/4885ACE2 2618/4885BLM 2257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.