SCHEMBL631769

SCHEMBL631769

Oc1ccc(-c2cccc3ccccc23)c(O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.56
ESR2 Q92731 3/20 0.51
ESR1 P03372 2/20 0.51
CYP1A2 P05177 2/20 0.50
NQO2 P16083 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
DHODH Q02127 1/20 0.49
LMNA P02545 1/20 0.47
CYP17A1 P05093 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP11B1 P15538 1/20 0.46
CYP11B2 P19099 1/20 0.46
MCL1 Q07820 1/20 0.46
ACMSD Q8TDX5 1/20 0.46
TLR8 Q9NR97 1/20 0.46
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28994302 0.88 TLR8 (0.58) ALOX5ESR2ESR1CYP1A2NQO2
SCHEMBL93762 0.86 ESR2 (0.50) ALOX5ESR2ESR1CYP1A2NQO2
SCHEMBL13492510 0.86 ESR2 (0.54) ESR2ESR1CYP1A2MEN1KMT2A
SCHEMBL6030742 0.85 ESR1 (0.50) ALOX5ESR2ESR1CYP1A2NQO2
SCHEMBL6031344 0.85 ESR1 (0.50) ALOX5ESR2ESR1CYP1A2NQO2
Betanaphthol SCHEMBL28453992 0.84 CYP1A2 (0.68) ESR2ESR1CYP1A2NQO2MEN1
SCHEMBL18347040 0.83 ESR1 (0.48) ALOX5ESR2ESR1CYP1A2MEN1
SCHEMBL217637 0.83 CYP1A2 (0.65) CYP1A2MEN1KMT2ACYP3A4MCL1
SCHEMBL30214159 0.83 CYP1A2 (0.65) CYP1A2MEN1KMT2ACYP3A4MCL1
SCHEMBL26153496 0.83 CYP1A2 (0.58) ESR2ESR1CYP1A2NQO2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1441011-B1 Energy transfer dye containing an aromatic-substituted xanthene dye as donor dye and/or acceptor dye LIFE TECHNOLOGIES CORP (US) 2012-02-22 EP disclosed