Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030742 | 1.00 | ESR1 (0.50) | ESR1ESR2ALOX5CYP17A1CYP3A4 | |
| SCHEMBL13851817 | 0.87 | ALOX5 (0.44) | ESR1ESR2ALOX5MEN1KMT2A | |
| SCHEMBL13851819 | 0.87 | ALOX5 (0.44) | ESR1ESR2ALOX5MEN1KMT2A | |
| SCHEMBL15147215 | 0.86 | ESR1 (0.53) | ESR1ESR2ALOX5CYP3A4MEN1 | |
| SCHEMBL6030531 | 0.85 | CYP1A2 (0.56) | MEN1KMT2ACYP1A2NTRK1POLB | |
| SCHEMBL631769 | 0.85 | ALOX5 (0.56) | ESR1ESR2ALOX5CYP17A1CYP3A4 | |
| SCHEMBL18913903 | 0.83 | SMN1; SMN2 (0.57) | ESR1ESR2ALOX5MEN1KMT2A | |
| SCHEMBL15147233 | 0.83 | KMT2A (0.45) | MEN1KMT2ACYP1A2MCL1ACMSD | |
| SCHEMBL13851823 | 0.82 | ALDH1A1 (0.41) | ESR1ESR2ALOX5CYP17A1CYP3A4 | |
| SCHEMBL12914336 | 0.81 | ALDH1A1 (0.47) | CYP3A4CYP11B2CYP1A2GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463774-B1 | NAPHTHYLTRIAZINES AS STABILIZERS FOR ORGANIC MATERIAL | BASF SE (DE) | 2013-07-31 | — | — | EP | disclosed |
| EP-1463774-B1 | NAPHTHYLTRIAZINES AS STABILIZERS FOR ORGANIC MATERIAL | BASF SE (DE) | 2013-07-31 | — | — | EP | disclosed |
| US-7087753-B2 | Naphthyltriazines as stabilizers for organic material | CIBA SPECIALTY CHEMICALS CORP. (US) | 2006-08-08 | — | — | US | disclosed |
| US-20050169859-A1 | Naphthyltriazines as stabilizers for organic material | TOAN VIEN V (CH) | 2005-08-04 | — | — | US | disclosed |
| US-20050038245-A1 | Naphthyltriazines as stabilizers for organic material | CIBA SPECIALTY CHEMICALS CORP. | 2005-02-17 | — | — | US | disclosed |
| EP-1463774-A1 | NAPHTHYLTRIAZINES AS STABILIZERS FOR ORGANIC MATERIAL | Ciba SC Holding AG (CH) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003035734-A1 | NAPHTHYLTRIAZINES AS STABILIZERS FOR ORGANIC MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038245-A1 | Naphthyltriazines as stabilizers for organic material | POT1, TYR, H1-2 | ESR1 852/4885ESR2 715/4885ALOX5 3138/4885 |
| US-20050169859-A1 | Naphthyltriazines as stabilizers for organic material | POT1, H1-2, TYR | ESR1 1006/4885ESR2 626/4885ALOX5 3153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.