⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18227146 | 0.86 | — | — | |
| SCHEMBL7715777 | 0.86 | — | — | |
| SCHEMBL2638699 | 0.86 | — | — | |
| SCHEMBL4599756 | 0.86 | — | — | |
| SCHEMBL20581663 | 0.86 | — | — | |
| SCHEMBL3855818 | 0.86 | — | — | |
| SCHEMBL2278783 | 0.86 | — | — | |
| SCHEMBL3852808 | 0.86 | — | — | |
| SCHEMBL2638694 | 0.86 | — | — | |
| SCHEMBL708051 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240425857-A1 | Means and Methods for Chronic Wound Healing | VIB VZW (BE) | 2024-12-26 | — | — | US | disclosed |
| US-20240382506-A1 | Means and Methods to Regulate Gut Dysbiosis | UNIVERSITEIT GENT (BE) | 2024-11-21 | — | — | US | disclosed |
| EP-4423269-A2 | MEANS AND METHODS FOR CHRONIC WOUND HEALING | VIB VZW (BE) | 2024-09-04 | — | — | EP | disclosed |
| EP-3523433-B1 | MEANS AND METHODS TO TREAT INFLAMMATORY DISEASES | VIB VZW (BE) | 2024-05-08 | — | — | EP | disclosed |
| EP-4355877-A1 | MEANS AND METHODS TO REGULATE GUT DYSBIOSIS | VIB VZW (BE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2023073046-A2 | MEANS AND METHODS FOR CHRONIC WOUND HEALING | VIB VZW (BE) | 2023-05-04 | — | — | WO | disclosed |
| WO-2022263678-A1 | MEANS AND METHODS TO REGULATE GUT DYSBIOSIS | VIB VZW (BE) | 2022-12-22 | — | — | WO | disclosed |
| US-11466270-B2 | Means and methods to treat inflammatory diseases | VIB VZW (BE) | 2022-10-11 | — | — | US | disclosed |
| US-20220313697-A1 | NEK6 Inhibition to Treat ALS and FTD | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2022-10-06 | — | — | US | disclosed |
| WO-2022199804-A1 | NEK6 INHIBITION TO TREAT ALS AND FTD | VIB VZW (BE) | 2022-09-29 | — | — | WO | disclosed |
| EP-3976055-A1 | COMBINATIONS OF THERAPEUTIC AGENTS FOR TREATING UVEAL MELANOMA | Universiteit Gent (BE) | 2022-04-06 | — | — | EP | disclosed |
| EP-3746555-B1 | INHIBITION OF A LNCRNA FOR TREATMENT OF NEUROBLASTOMA | UNIV GENT (BE) | 2022-03-30 | — | — | EP | disclosed |
| US-6967247-B2 | Deprotection of phosphorus in oligonucleotide synthesis | ISIS PHARMACEUTICALS, INC. (US) | 2005-11-22 | — | — | US | disclosed |
| US-6965041-B1 | N-acylphosphoramidites and their use in oligonucleotide synthesis | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-11-15 | — | — | US | disclosed |
| US-6762298-B2 | DEPROTECTING AN OLIGONUCLEOTIDE BY HEATING IN A FLUID, WHERE THE PHOSPHORUS ATOM IS O-PROTECTED WITH A THERMOLABILE GROUP SUCH AS (PYRROLIDIN-1-ONE-1-YL)ALKYL; SYNTHESIS OF OLIGONUCLEOTIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2004-07-13 | — | — | US | disclosed |
| US-20040024194-A1 | Deprotection of phosphorus in oligonucleotide synthesis | ISIS PHARMACEUTICALS, INC. | 2004-02-05 | — | — | US | disclosed |
| WO-2004009612-A1 | DEPROTECTION OF PHOSPHORUS IN OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS, INC. (US) | 2004-01-29 | — | — | WO | disclosed |
| EP-1163251-A1 | N-ACYLPHOSPHORAMIDITES AND THEIR USE IN OLIGONUCLEOTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2001-12-19 | — | — | EP | disclosed |
| US-20010044529-A1 | Thermolabile phosphorus protecting groups, associated intermediates and methods of use | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-11-22 | — | — | US | disclosed |
| WO-2000056749-A1 | N-ACYLPHOSPHORAMIDITES AND THEIR USE IN OLIGONUCLEOTIDE SYNTHESIS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2000-09-28 | — | — | WO | disclosed |