Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 18/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 15/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 15/20 | 0.53 |
| ▸ | GPR183 | P32249 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196764 | 0.85 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL27557312 | 0.85 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL6318378 | 0.79 | PGR (0.38) | — | |
| SCHEMBL6318377 | 0.77 | ITGAL (0.52) | ITGALITGB2ICAM1GPR183 | |
| SCHEMBL7613230 | 0.73 | ITGAL (0.91) | ITGALITGB2ICAM1 | |
| SCHEMBL27473569 | 0.73 | ITGAL (0.91) | ITGALITGB2ICAM1 | |
| SCHEMBL5830866 | 0.70 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL7647365 | 0.70 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL5836088 | 0.70 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL6200166 | 0.69 | ITGAL (0.72) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |