Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 8/20 | 0.45 |
| ▸ | ITGB2 | P05107 | 5/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.45 |
| ▸ | HTR2C | P28335 | 6/20 | 0.42 |
| ▸ | HTR2B | P41595 | 6/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310664 | 0.92 | ITGAL (0.44) | ITGALITGB2ICAM1HTR2CHTR2B | |
| SCHEMBL6199471 | 0.84 | ITGAL (0.50) | ITGALITGB2ICAM1HPGD | |
| SCHEMBL6312233 | 0.84 | HPGD (0.53) | ITGALITGB2ICAM1HPGD | |
| SCHEMBL6202393 | 0.84 | ITGAL (0.47) | ITGALITGB2ICAM1HPGD | |
| SCHEMBL6318688 | 0.81 | ITGAL (0.69) | ITGALITGB2ICAM1HTR2CHTR2B | |
| SCHEMBL6197144 | 0.81 | ITGAL (0.44) | ITGALITGB2ICAM1HPGD | |
| SCHEMBL6196146 | 0.81 | TDP1 (0.52) | ITGALITGB2ICAM1HPGD | |
| SCHEMBL6200934 | 0.80 | ITGAL (0.66) | ITGALITGB2ICAM1 | |
| SCHEMBL6308774 | 0.79 | ITGAL (0.51) | ITGALITGB2ICAM1HPGD | |
| SCHEMBL6311167 | 0.78 | ITGAL (0.54) | ITGALITGB2ICAM1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867203-B2 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-03-15 | — | — | US | disclosed |
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | disclosed |