Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 17/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27873707 | 0.90 | RBP4 (0.55) | RBP4POLB | |
| SCHEMBL631635 | 0.87 | RBP4 (0.61) | RBP4 | |
| SCHEMBL766253 | 0.83 | RBP4 (0.63) | RBP4POLB | |
| SCHEMBL766338 | 0.82 | RBP4 (0.56) | RBP4 | |
| SCHEMBL630875 | 0.82 | RBP4 (0.61) | RBP4POLB | |
| SCHEMBL630457 | 0.82 | RBP4 (0.61) | RBP4 | |
| SCHEMBL766226 | 0.81 | RBP4 (0.57) | RBP4 | |
| SCHEMBL631655 | 0.81 | RBP4 (0.50) | RBP4 | |
| SCHEMBL13154615 | 0.81 | RBP4 (0.54) | RBP4POLB | |
| SCHEMBL631656 | 0.79 | RBP4 (0.52) | RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459209-A | Derivatives of N-acyl-N' -phenylpiperazines for the prevention or treatment of diabetes (etc.) | TAKEDA PHARMACEUTICAL | 2012-05-16 | — | — | CN | disclosed |
| EP-2419413-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119992-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |