SCHEMBL6319985

SCHEMBL6319985

CC(C)(C)OC(=O)N1CCC[C@H]1COCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
ALOX5AP P20292 1/20 0.41
FEN1 P39748 1/20 0.41
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
PDE8B O95263 1/20 0.39
OPRD1 P41143 1/20 0.39
ATM Q13315 2/20 0.39
NPC1 O15118 1/20 0.39
HCRTR2 O43614 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3774461 1.00 HSD17B10 (0.46) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL2568345 1.00 HSD17B10 (0.46) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL31218628 0.96 PDE8B (0.43) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL2560957 0.96 PDE8B (0.43) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL2569371 0.92 HSD17B10 (0.39) HSD17B10SMN1; SMN2ATM
SCHEMBL3768956 0.92 HSD17B10 (0.39) HSD17B10SMN1; SMN2ATM
SCHEMBL29039261 0.89 HSD17B10 (0.43) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL3771067 0.89 HSD17B10 (0.43) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL2490765 0.89 HSD17B10 (0.43) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL20399345 0.86 HSD17B10 (0.44) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050053736-A1 Cationic colloidal dispersion polymers for ink jet coatings MEADWESTVACO CORPORATION 2005-03-10 US claimed
US-20050053734-A1 Stabilizer-containing cationic colloidal dispersion polymers for ink jet coatings MEADWESTVACO CORPORATION 2005-03-10 US claimed
WO-2004060689-A1 POLYMER BLEND COMPOSITIONS MEADWESTVACO CORPORATION (US) 2004-07-22 WO claimed
US-6756129-B1 Polymer blend compositions MEADWESTVACO CORPORATION 2004-06-29 US claimed
US-20040121173-A1 POLYMER BLEND COMPOSITIONS WESTVACO CORPORATION, A CORPORATION OF THE STATE OF DELAWARE (US) 2004-06-24 US claimed
US-20020192438-A1 Stabilizer-containing cationic colloidal dispersion polymers for ink jet coatings WESTVACO CORPORATION 2002-12-19 US claimed
US-20020127376-A1 Cationic colloidal dispersion polymers for ink jet coatings WESTVACO CORPORATION (US) 2002-09-12 US claimed
US-20050255160-A1 Polymide resin dermal composition SOHO LABORATORIES, INC. 2005-11-17 US disclosed
EP-1184370-B1 Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 2005-09-14 EP disclosed
US-6939880-B2 Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 2005-09-06 US disclosed
US-20050053736-A1 Cationic colloidal dispersion polymers for ink jet coatings MEADWESTVACO CORPORATION 2005-03-10 US disclosed
US-20050053734-A1 Stabilizer-containing cationic colloidal dispersion polymers for ink jet coatings MEADWESTVACO CORPORATION 2005-03-10 US disclosed
US-6756129-B1 Polymer blend compositions MEADWESTVACO CORPORATION 2004-06-29 US disclosed
US-5977178-A Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 1999-11-02 US disclosed
US-5922770-A NOVEL COMPOUNDS THAT STIMULATE THE RELEASE OF GROWTH HORMONE FROM THE PITUITARY NOVO NORDISK A/S (DK) 1999-07-13 US disclosed
EP-0923539-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1999-06-23 EP disclosed
WO-1998058950-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1998-12-30 WO disclosed
EP-0869974-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1998-10-14 EP disclosed
WO-1998003473-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1998-01-29 WO disclosed
WO-1997023508-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-07-03 WO disclosed