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SCHEMBL29039261

SCHEMBL29039261

CC(C)(C)OC(=O)COC[C@@H]1CCCN1C(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ ALOX5AP P20292 1/20 0.41
▸ FEN1 P39748 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.40
▸ PDE8B O95263 1/20 0.39
▸ OPRD1 P41143 1/20 0.39
▸ ATM Q13315 2/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ TSHR P16473 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3771067 1.00 HSD17B10 (0.43) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL2490765 1.00 HSD17B10 (0.43) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL3763846 0.96 PDE8B (0.43) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL5160976 0.92 SMN1; SMN2 (0.37) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL3781269 0.92 HSD17B10 (0.36) HSD17B10SMN1; SMN2ALDH1A1ATM
SCHEMBL3781276 0.92 HSD17B10 (0.36) HSD17B10SMN1; SMN2ALDH1A1ATM
SCHEMBL6318180 0.90 KMT2A (0.43) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL2566481 0.89 HSD17B10 (0.38) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL2568345 0.89 HSD17B10 (0.46) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1
SCHEMBL3774461 0.89 HSD17B10 (0.46) HSD17B10SMN1; SMN2ALOX5APFEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-04-23 — — US disclosed
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2026-03-19 — — US disclosed
US-20250312471-A1 ANTIBODY-DRUG COMPLEX CONTAINING TOLL-LIKE RECEPTOR 7/8 DUAL AGONIST COMPOUND ASTELLAS PHARMA INC. (JP) 2025-10-09 — — US disclosed
US-12390536-B2 Antibody-drug complex containing toll-like receptor 7/8 dual agonist compound ASTELLAS PHARMA INC. (JP) 2025-08-19 — — US disclosed
EP-4566633-A1 ANTIBODY-DRUG COMPLEX CONTAINING TOLL-LIKE RECEPTOR 7/8 DUAL AGONIST COMPOUND Astellas Pharma, Inc. (JP) 2025-06-11 — — EP disclosed
US-20250025567-A1 ANTIBODY-DRUG COMPLEX CONTAINING TOLL-LIKE RECEPTOR 7/8 DUAL AGONIST COMPOUND ASTELLAS PHARMA INC. (JP) 2025-01-23 — — US disclosed
US-12134609-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-11-05 — — US disclosed
US-20240092760-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-03-21 — — US disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 — — US disclosed
EP-4208452-A1 QUINOLINE CGAS ANTAGONIST COMPOUNDS Immunesensor Therapeutics, Inc. (US) 2023-07-12 — — EP disclosed
CN-116234802-A Quinoline CGAS antagonist compounds 免疫传感器治疗股份有限公司 2023-06-06 — — CN disclosed
US-20230081291-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS IMMUNESENSOR THERAPEUTICS, INC. (US) 2023-03-16 — — US disclosed
WO-2022051634-A1 QUINOLINE CGAS ANTAGONIST COMPOUNDS IMMUNESENSOR THERAPEUTICS, INC. (US) 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390536-B2 Antibody-drug complex containing toll-like receptor 7/8 dual agonist compound TLR6, TLR5, TLR7 HSD17B10 4535/4885SMN1; SMN2 4288/4885ALOX5AP 3157/4885
US-20250312471-A1 ANTIBODY-DRUG COMPLEX CONTAINING TOLL-LIKE RECEPTOR 7/8 DUAL AGONIST COMPOUND TLR7, TLR1, TLR2 HSD17B10 1860/4885SMN1; SMN2 4238/4885ALOX5AP 4146/4885
US-20240092760-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS CGAS, GLS2, GLS HSD17B10 2690/4885SMN1; SMN2 2633/4885ALOX5AP 3765/4885
US-11873291-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS HSD17B10 2690/4885SMN1; SMN2 2633/4885ALOX5AP 3765/4885
US-20250025567-A1 ANTIBODY-DRUG COMPLEX CONTAINING TOLL-LIKE RECEPTOR 7/8 DUAL AGONIST COMPOUND TLR6, TLR5, TLR7 HSD17B10 4535/4885SMN1; SMN2 4288/4885ALOX5AP 3157/4885
US-12134609-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS HSD17B10 2690/4885SMN1; SMN2 2633/4885ALOX5AP 3765/4885
US-20230081291-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS CGAS, GLS2, GLS HSD17B10 2690/4885SMN1; SMN2 2633/4885ALOX5AP 3765/4885
US-20260078116-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, MCL1 HSD17B10 4362/4885SMN1; SMN2 958/4885ALOX5AP 4132/4885
US-20260109696-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS KRAS, MYC, NRAS HSD17B10 3043/4885SMN1; SMN2 1323/4885ALOX5AP 3806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.