Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 12/20 | 0.72 |
| ▸ | ESR1 | P03372 | 11/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.60 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.60 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31419103 | 0.90 | ESR2 (0.74) | ESR2ESR1CYP1A2ALOX5HSD17B1 | |
| SCHEMBL28819464 | 0.90 | ESR2 (0.74) | ESR2ESR1CYP1A2ALOX5HSD17B1 | |
| SCHEMBL29666588 | 0.90 | ESR2 (0.74) | ESR2ESR1CYP1A2ALOX5HSD17B1 | |
| SCHEMBL9456813 | 0.86 | ESR2 (0.70) | ESR2ESR1CYP1A2ALOX5HSD17B1 | |
| SCHEMBL599502 | 0.85 | ESR2 (0.68) | ESR2ESR1CYP1A2ALOX5HSD17B1 | |
| SCHEMBL3016027 | 0.84 | ESR2 (1.00) | ESR2ESR1CYP1A2ALOX5HSD17B1 | |
| SCHEMBL6419636 | 0.84 | ESR2 (0.55) | ESR2ESR1CYP1A2ALOX5HSD17B1 | |
| SCHEMBL30463004 | 0.83 | ESR2 (0.78) | ESR2ESR1CYP1A2ALOX5HSD17B1 | |
| SCHEMBL217638 | 0.83 | ESR2 (0.78) | ESR2ESR1CYP1A2ALOX5HSD17B1 | |
| SCHEMBL3107306 | 0.83 | ESR2 (0.83) | ESR2ESR1CYP1A2ALOX5HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441011-B1 | Energy transfer dye containing an aromatic-substituted xanthene dye as donor dye and/or acceptor dye | LIFE TECHNOLOGIES CORP (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-1441011-B1 | Energy transfer dye containing an aromatic-substituted xanthene dye as donor dye and/or acceptor dye | LIFE TECHNOLOGIES CORP (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-1441011-A1 | Energy transfer dye containing an aromatic-substituted xanthene dye as donor dye and/or acceptor dye | Applera Corporation (US) | 2004-07-28 | — | — | EP | disclosed |
| EP-1019453-B1 | AROMATIC-SUBSTITUTED XANTHENE DYES | APPLERA CORP (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-1019453-A1 | AROMATIC-SUBSTITUTED XANTHENE DYES | THE PERKIN-ELMER CORPORATION (US) | 2000-07-19 | — | — | EP | disclosed |
| US-6008379-A | USEFUL AS FLUORESCENT DYES FOR LABELING | THE PERKIN-ELMER CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |
| WO-1999016832-A1 | AROMATIC-SUBSTITUTED XANTHENE DYES | THE PERKIN-ELMER CORPORATION (US) | 1999-04-08 | — | — | WO | disclosed |