SCHEMBL217638

SCHEMBL217638

Oc1ccccc1-c1ccc2ccccc2c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.78
HDAC4 P56524 1/20 0.61
HDAC2 Q92769 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
ALOX5 P09917 1/20 0.61
ESR1 P03372 2/20 0.57
GSTP1 P09211 1/20 0.57
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.54
BCL2L1 Q07817 1/20 0.54
HSD17B10 Q99714 1/20 0.54
HSD17B1 P14061 2/20 0.53
HSD17B2 P37059 2/20 0.53
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
ACMSD Q8TDX5 1/20 0.50
APP P05067 1/20 0.50
CYP1A2 P05177 1/20 0.48
MIF P14174 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30463004 1.00 ESR2 (0.78) ESR2HDAC4HDAC2HDAC8ALOX5
SCHEMBL27616562 0.94 ESR2 (0.75) ESR2HDAC4HDAC2HDAC8ALOX5
SCHEMBL3016027 0.88 ESR2 (1.00) ESR2ALOX5ESR1ALDH1A1HPGD
SCHEMBL14283894 0.86 ALOX5 (0.65) ESR2HDAC4HDAC2HDAC8ALOX5
SCHEMBL19211556 0.86 HDAC4 (0.66) ESR2HDAC4HDAC2HDAC8ALOX5
SCHEMBL17500075 0.85 ALOX5 (0.70) ESR2HDAC4HDAC2HDAC8ALOX5
SCHEMBL28988352 0.84 ALOX5 (0.63) ESR2HDAC4HDAC2HDAC8ALOX5
SCHEMBL29204860 0.84 ESR2 (0.58) ESR2HDAC4HDAC2HDAC8ALOX5
SCHEMBL27582824 0.84 ESR2 (0.62) ESR2HDAC4HDAC2HDAC8ESR1
SCHEMBL16812111 0.84 HDAC4 (0.64) ESR2HDAC4HDAC2HDAC8ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118702881-A Method for continuously preparing phenolic resin 山东圣泉新材料股份有限公司 2024-09-27 CN claimed
CN-117776963-A Synthesis method of phenol by diazotization 新疆大学 2024-03-29 CN claimed
CN-106632239-B A kind of isolonglifolane ketone group hexahydro quinazoline -2- amine schiff's base type fluorescent material and its synthetic method and application 南京林业大学 2019-04-12 CN claimed
CN-108697709-A Methods for treating huntington's disease PTC医疗公司 2018-10-23 CN claimed
US-20090284698-A1 Ink composition, color filter manufactured by using the same, and display device comprising the same LG CHEM., LTD. (KR) 2009-11-19 US claimed
US-7303855-B2 Photoresist undercoat-forming material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2007-12-04 US claimed
US-20060019195-A1 Photoresist undercoat-forming material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-01-26 US claimed
EP-4184248-B1 COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND AND POLYMER FOR FORMING ORGANIC FILM SHINETSU CHEMICAL CO (JP) 2026-04-15 EP disclosed
US-12590173-B2 Composition, pattern forming method, semiconductor device, and method for manufacturing semiconductor device KIOXIA CORPORATION (JP) 2026-03-31 US disclosed
US-12584023-B2 Composition for forming organic film, patterning process, and compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-24 US disclosed
EP-4398037-B1 COMPOUND FOR FORMING METAL-CONTAINING FILM, COMPOSITION FOR FORMING METAL-CONTAINING FILM, AND PATTERNING PROCESS SHINETSU CHEMICAL CO (JP) 2026-01-21 EP disclosed
EP-4660703-A2 METAL-CONTAINING FILM PATTERNING PROCESS Shin-Etsu Chemical Co., Ltd. (JP) 2025-12-10 EP disclosed
EP-4239408-B1 COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND SHINETSU CHEMICAL CO (JP) 2025-12-10 EP disclosed
US-4457874-A DISPERSANTS IN HYDRAULIC CEMENTS DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1984-07-03 US disclosed
EP-0073606-A1 Condensation products of aromatic sulphonic acids with formaldehyde DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1983-03-09 EP disclosed
US-4296948-A A LAYER OF MIXED PHENOLFORMALDEHYDE RESIN AND ACTIVE SILICIC ACID AND TITANIUM DIOXIDE; DISCOLORATION INHIBITION MITSUBISHI PAPER MILLS, LTD. (JP) 1981-10-27 US disclosed
US-4064179-A CHEMICAL INTERMEDIATES GENERAL ELECTRIC COMPANY (US) 1977-12-20 US disclosed
US-4056512-A COMPOSITION COMPRISING PHENOLIC RESINS AND CURING AMOUNTS TRIAZA PHOSPHAADAMANTANE COMPOUNDS HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-11-01 US disclosed
US-3965182-A Preparation of aniline from phenol and ammonia ETHYL CORPORATION (US) 1976-06-22 US disclosed
US-3952063-A Process for the preparation of an organomercaptophenol from sulfur, a phenol, and an activated olefin or an epoxy compound GENERAL ELECTRIC COMPANY (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584023-B2 Composition for forming organic film, patterning process, and compound F12, MLX, F11 ESR2 2260/4885HDAC4 4053/4885HDAC2 3481/4885
US-12590173-B2 Composition, pattern forming method, semiconductor device, and method for manufacturing semiconductor device TET2, SDC2, TST ESR2 2468/4885HDAC4 4784/4885HDAC2 4517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.