Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325006 | 0.87 | KMT2A (0.41) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6322766 | 0.82 | KMT2A (0.40) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6323840 | 0.81 | KMT2A (0.36) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL8692415 | 0.81 | KMT2A (0.42) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6325702 | 0.81 | KMT2A (0.42) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6280223 | 0.80 | ADORA2A (0.50) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6321175 | 0.80 | ADORA2A (0.46) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6323500 | 0.79 | KMT2A (0.42) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6324085 | 0.79 | ADORA2A (0.39) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6322314 | 0.77 | KMT2A (0.36) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872690-B2 | Herbicidal 2-alkynyl-pyri (mi) dines | WYETH (US) | 2005-03-29 | — | — | US | claimed |
| US-6872690-B2 | Herbicidal 2-alkynyl-pyri (mi) dines | WYETH (US) | 2005-03-29 | — | — | US | disclosed |
| US-20030073581-A1 | Herbicidal 2-alkynyl-pyri (mi) dines | WYETH | 2003-04-17 | — | — | US | disclosed |
| EP-1238586-A1 | Herbicidal 2-alkynyl-pyri(mi)dines | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073581-A1 | Herbicidal 2-alkynyl-pyri (mi) dines | DDT, AOX1, RIOX2 | KMT2A 1361/4885ADORA2A 2200/4885ADORA1 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.