SCHEMBL6322148

SCHEMBL6322148

CSc1cc(Br)c(SC)cc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5776026 0.81 POLB (0.38)
SCHEMBL16004957 0.81 ALOX15 (0.31)
SCHEMBL12320519 0.75 CYP2D6 (0.35)
SCHEMBL6604093 0.75 CA12 (0.42)
SCHEMBL8492110 0.75 KMT2A (0.43)
SCHEMBL2645981 0.75 ALOX15 (0.42)
SCHEMBL3465193 0.74 SMN1; SMN2 (0.37)
SCHEMBL12320835 0.74 CYP2D6 (0.34)
SCHEMBL2125230 0.73 MAPT (0.41)
SCHEMBL24769695 0.72 NQO2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107693505-B Oil-water double-soluble ROS sensitive nanoparticle and preparation method thereof 上海长海医院 2020-11-27 CN disclosed
US-20050258398-A1 Dithia-s-indacene derivative TAKASAGO INTERNATIONAL CORPORATION 2005-11-24 US disclosed
EP-1027398-B1 LIGHT-EMITTING DENDRIMERS AND DEVICES ISIS INNOVATION (GB) 2004-06-09 EP disclosed
US-6720093-B2 DEVICE INCORPORATING AS, OR IN, ITS LIGHT-EMITTING ELEMENT LUMINESCENT COMPOUND INCLUDING CONJUGATED DENDRITIC MOLECULAR STRUCTURE COMPRISING GROUPS SELECTED FROM ARYL AND HETEROARYL GROUPS AND ALKENYL GROUPS CONNECTED TO EACH OTHER CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2004-04-13 US disclosed
US-20030165716-A1 Dendrimers according to present invention which can be used for incorporation into light emitting devices have core and/or branches comprising electroluminescent or charge-transporting chromophores (conjugated units) CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2003-09-04 US disclosed
US-6558818-B1 Light-emitting dendrimers and devices ISIS INNOVATION LTD. (GB) 2003-05-06 US disclosed